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Yanhe Lue
Researcher at Los Angeles Biomedical Research Institute
Publications - 77
Citations - 3370
Yanhe Lue is an academic researcher from Los Angeles Biomedical Research Institute. The author has contributed to research in topics: Germ cell & Apoptosis. The author has an hindex of 33, co-authored 75 publications receiving 3116 citations. Previous affiliations of Yanhe Lue include University of California, Davis & University of California, Los Angeles.
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Journal ArticleDOI
Key apoptotic pathways for heat-induced programmed germ cell death in the testis.
Amiya P. Sinha Hikim,Yanhe Lue,Cindy M. Yamamoto,Yanira Vera,Susana Rodriguez,Pauline H. Yen,Kevin Soeng,Christina Wang,Ronald S. Swerdloff +8 more
TL;DR: Results demonstrate that the mitochondria- and possibly also endoplasmic reticulum-dependent pathways are the key apoptotic pathways for heat-induced germ cell death in the testis.
Journal ArticleDOI
Deciphering the pathways of germ cell apoptosis in the testis.
Amiya P. Sinha Hikim,Yanhe Lue,Maruja Diaz-Romero,Pauline H. Yen,Christina Wang,Ronald S. Swerdloff +5 more
TL;DR: It is demonstrated that the mitochondria- and possibly also ER-dependent pathways are the key apoptotic pathways for heat induced germ cell death in the testis.
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Spontaneous Germ Cell Apoptosis in Humans: Evidence for Ethnic Differences in the Susceptibility of Germ Cells to Programmed Cell Death
Amiya P. Sinha Hikim,Christina Wang,Yanhe Lue,Larry Johnson,Xing-Hai Wang,Ronald S. Swerdloff +5 more
TL;DR: The results suggest that germ cell death during normal spermatogenesis in men occurs via apoptosis and provide evidence for ethnic differences in the inherent susceptibility of germ cells to programmed cell death.
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Significance of apoptosis in the temporal and stage-specific loss of germ cells in the adult rat after gonadotropin deprivation
A. P. Sinha Hikim,Tripathi B. Rajavashisth,I Sinha Hikim,Yanhe Lue,Juan J. Bonavera,Andrew Leung,Christina Wang,Ronald S. Swerdloff +7 more
TL;DR: In situ analysis of germ cell apoptosis fully corroborated the observed increase in the degree of DNA fragmentation with time and also revealed a stage-related activation of apoptosis of specific germ cells, strongly supporting the concept that germ cell death after removal of hormonal support in the adult rat occurs almost exclusively via apoptosis.
Journal ArticleDOI
Fate of Bone Marrow Stem Cells Transplanted into the Testis : Potential Implication for Men with Testicular Failure
Yanhe Lue,Krista Erkkilä,Peter Liu,Kimberley Ma,Christina Wang,Amiya P. Sinha Hikim,Ronald S. Swerdloff +6 more
TL;DR: It is concluded that adult bone marrow cells, in a favorable testicular environment, differentiate into somatic and germ cell lineages and the resident neighboring cells in the recipient testis may control site-appropriate stem cell differentiation.