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Yanyan Wang
Researcher at University of Illinois at Urbana–Champaign
Publications - 17
Citations - 3836
Yanyan Wang is an academic researcher from University of Illinois at Urbana–Champaign. The author has contributed to research in topics: Dopamine receptor D2 & Long-term potentiation. The author has an hindex of 12, co-authored 16 publications receiving 3704 citations. Previous affiliations of Yanyan Wang include University of Pennsylvania & Salk Institute for Biological Studies.
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Journal ArticleDOI
Deficient Hippocampal Long-Term Potentiation in α-Calcium-Calmodulin Kinase II Mutant Mice
Alcino J. Silva,Alcino J. Silva,Charles F. Stevens,Charles F. Stevens,Susumu Tonegawa,Susumu Tonegawa,Yanyan Wang,Yanyan Wang +7 more
TL;DR: W Whole cell recordings reveal that postsynaptic mechanisms, including N-methyl-D-aspartate (NMDA) receptor function, are intact and are therefore a suitable model for studying the relation between LTP and learning processes.
Journal ArticleDOI
Facilitation and depression at single central synapses
Charles F. Stevens,Yanyan Wang +1 more
TL;DR: Using whole-cell recording from CA1 hippocampal pyramidal neurons and minimal stimulation of Schaffer collaterals, the majority of stimulus-evoked synaptic currents are produced by a single synapse under the conditions of minimal stimulation, even if multiple synapses are actually present.
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Mutant mice and neuroscience: Recommendations concerning genetic background
Alcino J. Silva,Elizabeth M. Simpson,Joseph S. Takahashi,Hans-Peter Lipp,Shigetada Nakanishi,Jeanne M. Wehner,Karl Peter Giese,Tim Tully,Ted Abel,Paul F. Chapman,Kevin Fox,Seth G. N. Grant,Shigeyoshi Itohara,Richard Lathe,Mark Mayford,James O. McNamara,Roger J. Morris,Marina R. Picciotto,John C. Roder,Hee-Sup Shin,Paul A. Slesinger,Daniel R. Storm,Michael P. Stryker,Susumu Tonegawa,Yanyan Wang,David P. Wolfer +25 more
TL;DR: The following scientists made significant contributions to the recommendations in the report on climate change made by the United Nations Educational, Scientific and Cultural Organization (UNESCO) in 2016.
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Changes in reliability of synaptic function as a mechanism for plasticity
Charles F. Stevens,Yanyan Wang +1 more
TL;DR: It is found that LTP increases synaptic reliability, and LTD decreases it, both without a change in the size of those postsynaptic currents that do occur, thus LTD is a functional inverse of LTP.
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Reversal of long-term potentiation by inhibitors of haem oxygenase.
Charles F. Stevens,Yanyan Wang +1 more
TL;DR: The effect on LTP of inhibitors of the enzyme haem oxygenase-2, which catalyses the production of carbon monoxide in the brain, is investigated, finding that these inhibitors prevent the induction of LTP and have no effect on one form of long-term depression.