Y
Yanze Liu
Researcher at Peking Union Medical College
Publications - 28
Citations - 1320
Yanze Liu is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Interferon & T cell. The author has an hindex of 13, co-authored 25 publications receiving 1193 citations. Previous affiliations of Yanze Liu include Harvard University & Chinese Ministry of Education.
Papers
More filters
Journal ArticleDOI
Identification of hepatoprotective flavonolignans from silymarin
Stephen J. Polyak,Chihiro Morishima,Volker Lohmann,Sampa Pal,David Y.W. Lee,Yanze Liu,Tyler N. Graf,Nicholas H. Oberlies +7 more
TL;DR: The data suggest that sily marin- and silymarin-derived compounds may influence HCV disease course in some patients.
Journal ArticleDOI
Molecular structure and stereochemistry of silybin a, silybin b, isosilybin a, and isosilybin b, isolated from silybum marianum (milk thistle)
David Y.W. Lee,Yanze Liu +1 more
TL;DR: Two pairs of diastereoisomeric flavonolignans were successfully separated from Silybum marianum by sequential silica gel column chromatography, preparative reversed-phase HPLC, and recrystallization.
Journal ArticleDOI
Inhibition of T-Cell Inflammatory Cytokines, Hepatocyte NF-κB Signaling, and HCV Infection by Standardized Silymarin
Stephen J. Polyak,Chihiro Morishima,Margaret C. Shuhart,Chia C. Wang,Yanze Liu,David Y.W. Lee +5 more
TL;DR: The data indicate that Silymarin exerts anti-inflammatory and antiviral effects, and suggest that complementary and alternative medicine-based approaches may assist in the management of patients with chronic hepatitis C.
Journal ArticleDOI
Silymarin protects against acute ethanol-induced hepatotoxicity in mice.
Zhenyuan Song,Ion Deaciuc,Ion Deaciuc,Ming Song,Ming Song,David Y.W. Lee,Yanze Liu,Xiaosheng Ji,Craig J. McClain,Craig J. McClain,Craig J. McClain +10 more
TL;DR: Silymarin protects against the liver injury caused by acute EtOH administration and may be developed as an effective therapeutic agent for alcohol-induced liver disease by its antioxidative stress and anti-inflammatory features.
Journal ArticleDOI
Silymarin inhibits in vitro T-cell proliferation and cytokine production in hepatitis C virus infection.
Chihiro Morishima,Margaret C. Shuhart,Chia C. Wang,Denise M. Paschal,Minjun C. Apodaca,Yanze Liu,Derek D. Sloan,Derek D. Sloan,Tyler N. Graf,Nicholas H. Oberlies,David Y.W. Lee,Keith R. Jerome,Keith R. Jerome,Stephen J. Polyak +13 more
TL;DR: Silymarin's ability to inhibit the proliferation and proinflammatory cytokine secretion of T cells, combined with its previously described antiviral effect, suggests a possible mechanism of action that could lead to clinical benefit during HCV infection.