Y
Yasuo Horie
Researcher at Ontario Institute for Cancer Research
Publications - 3
Citations - 1473
Yasuo Horie is an academic researcher from Ontario Institute for Cancer Research. The author has contributed to research in topics: NOD1 & Chemokine. The author has an hindex of 2, co-authored 3 publications receiving 1409 citations.
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Journal ArticleDOI
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid.
Mathias Chamaillard,Masahito Hashimoto,Yasuo Horie,Junya Masumoto,Su Qiu,Lisa Saab,Yasunori Ogura,Akiko Kawasaki,Koichi Fukase,Shoichi Kusumoto,Miguel A. Valvano,Simon J. Foster,Tak W. Mak,Gabriel Núñez,Naohiro Inohara +14 more
TL;DR: It is reported that NOD1 mediates selective recognition of bacteria through detection of iE-DAP-containing peptidoglycan derived primarily from Gram-negative bacteria.
Journal ArticleDOI
Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo.
Junya Masumoto,Kangkang Yang,Sooryanarayana Varambally,Mizuho Hasegawa,Scott A. Tomlins,Su Qiu,Yukari Fujimoto,Akiko Kawasaki,Simon J. Foster,Yasuo Horie,Tak W. Mak,Gabriel Núñez,Arul M. Chinnaiyan,Koichi Fukase,Naohiro Inohara +14 more
TL;DR: Results indicate that Nod1 functions as a pathogen recognition molecule to induce expression of molecules involved in the early stages of the innate immune response.
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Shigehisa Yanagi,Hiroyuki Kishimoto,Kohichi Kawahara,Takehiko Sasaki,Masato Sasaki,Miki Nishio,Nobuyuki Yajima,Koichi Hamada,Yasuo Horie,Hiroshi Kubo,Jeffrey A. Whitsett,Tak Wah Mak,Toru Nakano,Masamitsu Nakazato,Akira Suzuki +14 more