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Yasuyuki Ishii
Researcher at Juntendo University
Publications - 129
Citations - 3108
Yasuyuki Ishii is an academic researcher from Juntendo University. The author has contributed to research in topics: Electrode & Natural killer T cell. The author has an hindex of 29, co-authored 128 publications receiving 2954 citations. Previous affiliations of Yasuyuki Ishii include Merck & Co. & National Institute of Advanced Industrial Science and Technology.
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Journal ArticleDOI
Molecular cloning and functional expression of a cDNA encoding glycosylation-inhibiting factor.
Toshifumi Mikayama,Tatsumi Nakano,Hideho Gomi,Yukimitsu Nakagawa,Yun Cai Liu,Masahiro Sato,Akihiro Iwamatsu,Yasuyuki Ishii,Weishui Y. Weiser,Kimishige Ishizaka +9 more
TL;DR: Results indicate that the 13-kDa peptide represents recombinant GIF, but posttranslational modification of the peptide is important for generation of the bioactivity.
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Prediction of hepatic clearance and availability by cryopreserved human hepatocytes: an application of serum incubation method.
TL;DR: Data suggested that the calibration of inherent interindividual variation of metabolic activities among different cryopreserved preparations of human hepatocytes to obtain the empirical scaling factor was an essential step for more reliable and quantitative prediction of in vivo metabolic activity in humans.
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L-152,804: orally active and selective neuropeptide Y Y5 receptor antagonist.
Akio Kanatani,Akane Ishihara,Hisashi Iwaasa,Kayo Nakamura,Osamu Okamoto,Masayasu Hidaka,Junko Ito,Takahiro Fukuroda,Douglas J. MacNeil,Lex H.T. Van der Ploeg,Yasuyuki Ishii,Takayoshi Okabe,Takehiro Fukami,Masaki Ihara +13 more
TL;DR: It is suggested that L-152,804 is a selective and potent non-peptide Y5 antagonist with oral bioavailability and brain penetrability and represents a useful tool to address the physiological role of the Y5 receptor.
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Loss of Thioredoxin-Binding Protein-2/Vitamin D3 Up-Regulated Protein 1 in Human T-Cell Leukemia Virus Type I-Dependent T-Cell Transformation Implications for Adult T-Cell Leukemia Leukemogenesis
Yumiko Nishinaka,Akira Nishiyama,Hiroshi Masutani,Shinichi Oka,Kaimul Ahsan,Yukie Nakayama,Yasuyuki Ishii,Hajime Nakamura,Michiyuki Maeda,Junji Yodoi +9 more
TL;DR: The results suggest that TBP-2 plays a crucial role in the growth regulation of T cells and that the loss of T BP-2 expression in HTLV-I-infected T cells is one of the key events involved in the multistep progression of ATL leukemogenesis.
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IL-21-induced Bε cell apoptosis mediated by natural killer T cells suppresses IgE responses
Michishige Harada,Kumiko Magara-Koyanagi,Hiroshi Watarai,Yuko Nagata,Yasuyuki Ishii,Satoshi Kojo,Shigetoshi Horiguchi,Yoshitaka Okamoto,Toshinori Nakayama,Nobutaka Suzuki,Wen Chen Yeh,Shizuo Akira,Hiroshi Kitamura,Osamu Ohara,Ken-ichiro Seino,Masaru Taniguchi +15 more
TL;DR: It is demonstrated that natural killer T (NKT) cells in mice and humans play a crucial role in the BCG-induced suppression of IgE responses, providing new insight into the therapeutic effect of BCG in allergic diseases.