Y
Yi-Hao Weng
Researcher at Stanford University
Publications - 10
Citations - 616
Yi-Hao Weng is an academic researcher from Stanford University. The author has contributed to research in topics: Heme oxygenase & Heme. The author has an hindex of 6, co-authored 8 publications receiving 571 citations.
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Journal ArticleDOI
Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress.
Qing Lin,Sebastian Weis,Guang Yang,Yi-Hao Weng,Rachel Helston,Kimberly Rish,Ann Smith,Jessica Bordner,Tobias Polte,Frank Gaunitz,Phyllis A. Dennery,Phyllis A. Dennery +11 more
TL;DR: It is speculated that nuclear localization of HO-1 protein may serve to up-regulate genes that promote cytoprotection against oxidative stress after exposure to hypoxia and heme or heme/hemopexin.
Journal ArticleDOI
Maturational differences in lung NF-κB activation and their role in tolerance to hyperoxia
TL;DR: There are maturational differences in lung NF-kappaB activation and that enhanced NF- kappaB may serve to protect the neonatal lung from acute hyperoxic injury via inhibition of apoptosis, demonstrating that neonatal rodents are more tolerant to hyperoxia than adults.
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Interaction between Heme Oxygenase-1 and -2 Proteins *
TL;DR: It is speculated that this HO-1·HO-2 protein interaction may promote non-enzymatic functions of HO, which is suspected by the co-localization of these enzymes in the lung and regions of the brain.
Journal ArticleDOI
HO-1 expression in type II pneumocytes after transpulmonary gene delivery
TL;DR: A cell-specific effect of lung HO-1 overexpression in oxidative stress is demonstrated and the transpulmonary approach may prove useful in targeting gene expression to cells of the alveolar epithelium or to circumscribed areas of the lung.
Journal ArticleDOI
Developmental Expression of Heme Oxygenase in the Rat Lung
Phyllis A. Dennery,Christen S. Lee,Berendera S Ford,Yi-Hao Weng,Guang Yang,Pamela A. Rodgers +5 more
TL;DR: Lung heme content was inversely correlated with HO activity or protein as the highest heme values were seen in adults with the lowest HO activity, and in response to hyperoxia, HO-1 mRNA was induced only in the adult lungs.