Y
Yi Zheng
Researcher at Harvard University
Publications - 25
Citations - 1869
Yi Zheng is an academic researcher from Harvard University. The author has contributed to research in topics: Stroke & Ischemia. The author has an hindex of 14, co-authored 23 publications receiving 1620 citations. Previous affiliations of Yi Zheng include Tufts University & Massachusetts Institute of Technology.
Papers
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Journal ArticleDOI
Compact Biocompatible Quantum Dots Functionalized for Cellular Imaging
Wenhao Liu,Mark Howarth,Andrew B. Greytak,Yi Zheng,Daniel G. Nocera,Alice Y. Ting,Moungi G. Bawendi +6 more
TL;DR: A family of water-soluble quantum dots (QDs) that exhibit low nonspecific binding to cells, small hydrodynamic diameter, tunable surface charge, high quantum yield, and good solution stability across a wide pH range are presented.
Journal ArticleDOI
Monovalent, reduced-size quantum dots for imaging receptors on living cells.
Mark Howarth,Mark Howarth,Wenhao Liu,Sujiet Puthenveetil,Yi Zheng,Lisa F. Marshall,Michael M. Schmidt,K. Dane Wittrup,Moungi G. Bawendi,Alice Y. Ting +9 more
TL;DR: In this paper, a method to generate monovalent quantum dots (QDs) using agarose gel electrophoresis was described, which improved access of QD-labeled glutamate receptors to neuronal synapses, and monovalency prevented EphA3 tyrosine kinase activation.
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Supply-Demand Mismatch Transients in Susceptible Peri-infarct Hot Zones Explain the Origins of Spreading Injury Depolarizations
Daniel von Bornstädt,Daniel von Bornstädt,Thijs Houben,Thijs Houben,Jessica L. Seidel,Yi Zheng,Ergin Dilekoz,Ergin Dilekoz,Tao Qin,Nora Sandow,Sreekanth Kura,Katharina Eikermann-Haerter,Matthias Endres,David A. Boas,Michael A. Moskowitz,Eng H. Lo,Jens P. Dreier,Johannes Woitzik,Sava Sakadžić,Cenk Ayata +19 more
TL;DR: It is proposed that minimizing sensory stimulation and hypoxic or hypotensive transients in stroke and brain injury would reduce PID incidence and their adverse impact on outcome.
Journal ArticleDOI
Vagus nerve stimulation inhibits cortical spreading depression.
Shih Pin Chen,Ilknur Ay,Andreia Morais,Tao Qin,Yi Zheng,Homa Sadeghian,Fumiaki Oka,Bruce J. Simon,Katharina Eikermann-Haerter,Cenk Ayata +9 more
TL;DR: The findings provide a potential mechanism by which vagus nerve stimulation may be efficacious in migraine and suggest that susceptibility to spreading depression is a suitable platform to optimize its efficacy.
Journal ArticleDOI
Selective ROCK2 inhibition in focal cerebral ischemia
Jeong Hyun Lee,Yi Zheng,Daniel von Bornstädt,Ying Wei,Aygul Balcioglu,Ali Daneshmand,Nilufer Yalcin,Esther S. Yu,Fanny Herisson,Yahya B Atalay,Maya Hwewon Kim,Yong-Joo Ahn,Mustafa Balkaya,Paul Sweetnam,Olivier Schueller,Masha V Poyurovsky,Hyung-Hwan Kim,Eng H. Lo,Karen L. Furie,Cenk Ayata +19 more
TL;DR: Rho‐associated kinase (ROCK) is a key regulator of numerous processes in multiple cell types relevant in stroke pathophysiology and inhibitors have improved outcome in experimental models of acute ischemic or hemorrhagic stroke.