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Yifeng Zhou
Researcher at Soochow University (Suzhou)
Publications - 109
Citations - 5477
Yifeng Zhou is an academic researcher from Soochow University (Suzhou). The author has contributed to research in topics: Genotype & Lung cancer. The author has an hindex of 35, co-authored 90 publications receiving 4944 citations. Previous affiliations of Yifeng Zhou include Peking Union Medical College & Guangzhou Medical University.
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Journal ArticleDOI
Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/β-catenin pathway
Fang-Fang Li,Liyuan Zhang,Wei Li,Jieqiong Deng,Jian Zheng,Mingxing An,Jiachun Lu,Yifeng Zhou +7 more
TL;DR: Results indicate that cir-ITCH may have an inhibitory effect on ESCC by regulating the Wnt pathway.
Journal ArticleDOI
Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations
Chen Wu,Zhibin Hu,Zhonghu He,Wei Hua Jia,Feng Wang,Yifeng Zhou,Zhihua Liu,Qimin Zhan,Yu Liu,Dianke Yu,Kan Zhai,Jiang Chang,Yan Qiao,Guangfu Jin,Zhe Liu,Yuanyuan Shen,Chuanhai Guo,Jianhua Fu,Xiaoping Miao,Wen Tan,Hongbing Shen,Yang Ke,Yi Xin Zeng,Tangchun Wu,Dongxin Lin +24 more
TL;DR: Seven susceptibility loci on chromosomes 5q11, 6p21, 10q23, 12q24 and 21q22 confer their risks to ESCC in a gene-lifestyle interaction manner, with more pronounced risk enhancement seen in tobacco and alcohol users.
Journal ArticleDOI
A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1
Yongyong Shi,Zhibin Hu,Chen Wu,Juncheng Dai,H Li,Jing Dong,Meilin Wang,Xiaoping Miao,Yifeng Zhou,Feng Lu,Hanze Zhang,Lingmin Hu,Yue Jiang,Zhiqiang Li,Minjie Chu,Hongxia Ma,Jiaping Chen,Guangfu Jin,Wen Tan,Tangchun Wu,Zhengdong Zhang,Dongxin Lin,Hongbing Shen +22 more
TL;DR: A genome-wide association study in 3,279 individuals of Chinese descent found two new susceptibility loci for non-cardia gastric cancer at 5p13.1 and 3q13.31, and confirmed previously reported associations of rs2294008 and rs2976392 on 8q24, rs4072037 on 1q22 and rs13042395 on 20p13 with non- Cardia gastrics cancer susceptibility in the Han Chinese population.
Journal ArticleDOI
Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation
Jian Zheng,Xudong Huang,Wen Tan,Dianke Yu,Zhongli Du,Jiang Chang,Lixuan Wei,Yaling Han,Chengfeng Wang,Xu Che,Yifeng Zhou,Xiaoping Miao,Guoliang Jiang,Xianjun Yu,Xianghong Yang,Guangwen Cao,Chaohui Zuo,Zhao-Shen Li,Chunyou Wang,Siu Tim Cheung,Yongfeng Jia,Xiongwei Zheng,Hongbing Shen,Chen Wu,Dongxin Lin +24 more
TL;DR: A G>A change at rs11655237 in exon 4 of LINC00673 creates a target site for miR-1231 binding, which diminishes the effect of Linc00673 in an allele-specific manner and thus confers susceptibility to tumorigenesis.
Journal ArticleDOI
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions
Chen Wu,Chen Wu,Peter Kraft,Kan Zhai,Jiang Chang,Zhaoming Wang,Zhaoming Wang,Yun Li,Zhibin Hu,Zhonghu He,Wei Hua Jia,Christian C. Abnet,Liming Liang,Nan Hu,Xiaoping Miao,Yifeng Zhou,Zhihua Liu,Qimin Zhan,Yu Liu,Yan Qiao,Yuling Zhou,Guangfu Jin,Chuanhai Guo,Changdong Lu,Haijun Yang,Jianhua Fu,Dianke Yu,Neal D. Freedman,Ti Ding,Wen Tan,Alisa M. Goldstein,Tangchun Wu,Hongbing Shen,Yang Ke,Yi Xin Zeng,Stephen J. Chanock,Stephen J. Chanock,Philip R. Taylor,Dongxin Lin +38 more
TL;DR: A joint analysis showed that drinkers with both of the ADH1B and ALDH2 risk alleles had a fourfold increased risk for ESCC compared to drinkers without these risk allels, which underscores the direct genetic contribution to ESCC risk, as well as the genetic contribution through interaction with alcohol consumption.