Yilianys Pride

TL;DR: In this article, the authors performed scRNA-seq on nasopharyngeal swabs from 58 healthy and COVID-19 participants, and identified genes associated with susceptibility, resistance, or infection response.

TL;DR: The reduction in the density of CB-IR GABAergic neurons in the occipital cortex in depression is similar to that observed previously in the prefrontal cortex.

TL;DR: This work defines both protective and detrimental host responses to SARS-CoV-2, determines the direct viral targets of infection, and suggests that failed anti-viral epithelial immunity in the nasal mucosa may underlie the progression to severe COVID-19.

TL;DR: In this paper, the relationship between intestinal microbiota and SARS-CoV-2-mediated pathogenicity in a United States, majority African American cohort was investigated, where 16S rRNA sequencing and qPCR analysis was performed on fecal DNA/RNA.

TL;DR: It is suggested that infection of the oral cavity and nasopharynx (ONP) is an obligate step in its pathogenesis, suggesting that innate and adaptive immune responses in the oral epithelia are almost certainly involved in the defense against SARS-CoV-2 infection.