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Sarah C. Glover
Researcher at University of Mississippi Medical Center
Publications - 100
Citations - 2667
Sarah C. Glover is an academic researcher from University of Mississippi Medical Center. The author has contributed to research in topics: Inflammatory bowel disease & Medicine. The author has an hindex of 21, co-authored 85 publications receiving 1912 citations. Previous affiliations of Sarah C. Glover include Veterans Health Administration & University of Florida.
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Journal ArticleDOI
Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease.
Uma Mahadevan,Douglas C. Wolf,Marla Dubinsky,Antoine Cortot,Scott D. Lee,Corey A. Siegel,Thomas A. Ullman,Sarah C. Glover,Sarah C. Glover,John F. Valentine,David T. Rubin,Jocelyn Miller,Maria T. Abreu +12 more
TL;DR: CZP has the lowest level of placental transfer, based on levels measured in cords and infants at birth, of the drugs tested; the TNF antagonists IFX and ADA are transferred across the placenta and can be detected in babies at birth.
Journal ArticleDOI
Translocation of the 85-kDa Phospholipase A2 from Cytosol to the Nuclear Envelope in Rat Basophilic Leukemia Cells Stimulated with Calcium Ionophore or IgE/Antigen
TL;DR: The results suggest that the extent of membrane binding of cPLA2 correlates with the release of arachidonate and that the site of archidonate liberation is the nuclear envelope where many of the enzymes that oxygenate this fatty acid are located.
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Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number.
Jonathan J. Lyons,Xiaomin Yu,Jason D. Hughes,Quang T. Le,Ali Jamil,Yun Bai,Nancy Ho,Ming Zhao,Yihui Liu,Michael P. O'Connell,Neil N. Trivedi,Celeste Nelson,Thomas DiMaggio,Nina Jones,Helen F. Matthews,Katie L. Lewis,Andrew J. Oler,Ryan J. Carlson,Peter D. Arkwright,Celine Hong,Sherene Agama,Todd M. Wilson,Sofie Tucker,Yu Zhang,Joshua J McElwee,Maryland Pao,Sarah C. Glover,Marc E. Rothenberg,Robert J. Hohman,Kelly D. Stone,George H. Caughey,George H. Caughey,Theo Heller,Dean D. Metcalfe,Leslie G. Biesecker,Lawrence B. Schwartz,Joshua D. Milner +36 more
TL;DR: The identification of germline duplications and triplications in the TPSAB1 gene encoding α-tryptase that segregate with inherited increases in basal serum tryptase levels in 35 families presenting with associated multisystem complaints are reported.
Journal ArticleDOI
Interleukin 1β Mediates Intestinal Inflammation in Mice and Patients With Interleukin 10 Receptor Deficiency
Dror S. Shouval,Amlan Biswas,Amlan Biswas,Yu Hui Kang,Yu Hui Kang,Alexandra Griffith,Liza Konnikova,Liza Konnikova,Ivan D. Mascanfroni,Ivan D. Mascanfroni,Naresh Singh Redhu,Naresh Singh Redhu,Sandra M. Frei,Sandra M. Frei,Michael Field,Andria L. Doty,Jeff Goldsmith,Jeff Goldsmith,Atul K. Bhan,Anthony Loizides,Batia Weiss,Batia Weiss,Baruch Yerushalmi,Tadahiro Yanagi,Xiuli Lui,Francisco J. Quintana,Francisco J. Quintana,Aleixo M. Muise,Christoph Klein,Bruce H. Horwitz,Bruce H. Horwitz,Sarah C. Glover,Athos Bousvaros,Athos Bousvaros,Scott B. Snapper,Scott B. Snapper,Scott B. Snapper +36 more
TL;DR: The findings indicate that loss of IL10 signaling leads to intestinal inflammation, at least in part, through increased production of IL1 by innate immune cells, leading to activation of CD4+ T cells.
Journal ArticleDOI
Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19.
Carly G. K. Ziegler,Vincent N. Miao,Anna H. Owings,Andrew W. Navia,Ying Tang,Joshua D. Bromley,Peter Lotfy,Peter Lotfy,Meredith Sloan,Hannah Laird,Haley B. Williams,Micayla George,Micayla George,Micayla George,Riley S. Drake,Riley S. Drake,Riley S. Drake,Taylor Christian,Adam M. Parker,Campbell B Sindel,Molly W. Burger,Yilianys Pride,Mohammad H. Hasan,George E. Abraham,Michal Senitko,Tanya O. Robinson,Alex K. Shalek,Sarah C. Glover,Bruce H. Horwitz,Bruce H. Horwitz,Jose Ordovas-Montanes +30 more
TL;DR: In this article, the authors performed scRNA-seq on nasopharyngeal swabs from 58 healthy and COVID-19 participants, and identified genes associated with susceptibility, resistance, or infection response.