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Yingnan Zeng
Researcher at Xi'an Jiaotong University
Publications - 11
Citations - 108
Yingnan Zeng is an academic researcher from Xi'an Jiaotong University. The author has contributed to research in topics: Degranulation & Mast cell. The author has an hindex of 4, co-authored 11 publications receiving 37 citations.
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Journal ArticleDOI
Imperatorin ameliorates mast cell-mediated allergic airway inflammation by inhibiting MRGPRX2 and CamKII/ERK signaling pathway.
Nan Wang,Jue Wang,Yongjing Zhang,Yingnan Zeng,Shiling Hu,Haoyun Bai,Yajing Hou,Cheng Wang,Huaizhen He,Langchong He +9 more
TL;DR: In this article, the effect of IMP on MRGPRX2 related mast cell activation in mouse peritoneal MC (MPMC), Human Laboratory of Allergic Disease 2 MCs (LAD2 cells) and MRgprx2-expressing HEK293 cells was examined.
Journal ArticleDOI
Anti-pseudo-allergy effect of isoliquiritigenin is MRGPRX2-dependent
TL;DR: The finding that ISL could inhibit IgE-independent allergy, via the Mrgprx2 pathway provides a new insight into pseudo-allergy and its therapy.
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Dehydroandrographolide inhibits IgE-mediated anaphylactic reactions via calcium signaling pathway
Delu Che,Yajing Hou,Yingnan Zeng,Chaomei Li,Yongjing Zhang,Di Wei,Shiling Hu,Rui Liu,Hongli An,Yajun Wang,Tao Zhang +10 more
TL;DR: It is revealed that DA can inhibit allergic responses in vivo and in vitro, and it may be regarded as a novel P‐PLC&ggr; inhibitor for preventing mast cell‐immediate and delayed allergic diseases.
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Roxithromycin inhibits compound 48/80-induced pseudo-allergy via the MrgprX2 pathway both in vitro and in vivo.
TL;DR: ROX could inhibit pseudo-allergic reactions, and this effect involves the Ca2+/PLC/IP3 pathway of MrgprX2.
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Baicalin induces Mrgprb2-dependent pseudo-allergy in mice.
TL;DR: Baicalin was found to dose-dependently induce pseudo-allergy both in vitro and in vivo, and the role of Mrgprb2 in baicalin-induced allergy was evaluated.