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Yinyi Shi
Publications - 2
Citations - 245
Yinyi Shi is an academic researcher. The author has contributed to research in topics: Dipyridamole & ARDS. The author has an hindex of 2, co-authored 2 publications receiving 178 citations.
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Journal ArticleDOI
Potential therapeutic effects of dipyridamole in the severely ill patients with COVID-19.
Xiaoyan Liu,Zhe Li,Shuai Liu,Jing Sun,Zhanghua Chen,Min Jiang,Qingling Zhang,Yinghua Wei,Xin Wang,Yi-You Huang,Yinyi Shi,Yanhui Xu,Huifang Xian,Fan Bai,Changxing Ou,Bei Xiong,Andrew M. Lew,Jun Cui,Rongli Fang,Hui Huang,Jincun Zhao,Xuechuan Hong,Yuxia Zhang,Fuling Zhou,Hai-Bin Luo +24 more
TL;DR: An anticoagulation agent dipyridamole (DIP) in silico, which suppressed SARS-CoV-2 replication in vitro, was identified and associated with significantly decreased concentrations of D-dimers, increased lymphocyte and platelet recovery in the circulation, and markedly improved clinical outcomes in comparison to the control patients.
Posted ContentDOI
Therapeutic effects of dipyridamole on COVID-19 patients with coagulation dysfunction
Xiaoyan Liu,Zhe Li,Shuai Liu,Zhanghua Chen,Zhanghua Chen,Zhiyao Zhao,Yi-You Huang,Qingling Zhang,Jun Wang,Yinyi Shi,Yanhui Xu,Jing Sun,Huifang Xian,Rongli Fang,Fan Bai,Changxing Ou,Bei Xiong,Andrew M. Lew,Jun Cui,Hui Huang,Jincun Zhao,Xuechuan Hong,Xuechuan Hong,Yuxia Zhang,Fulin Zhou,Hai-Bin Luo +25 more
TL;DR: HCoV-19 infected patients could potentially benefit from DIP adjunctive therapy by reducing viral replication, suppressing hypercoagulability and enhancing immune recovery.