Yogesh Kumar

TL;DR: It is speculated that the molecular multiplicity of the C‐terminus (and intracellular loops) dictated by alternative exons may modulate or create additional interacting sites in a tissue‐specific manner.

TL;DR: The results suggest 1007YNMLCFGIY1015 possible participation in Slo1 plasmalemmal targeting and demonstrate its role as a main mechanism for caveolin-1 association withSlo1 potentially serving a dual role: (i) maintaining channels in intracellular compartments downsizing their surface expression and/or (ii) serving as anchor of plasma membrane resident channels to caveolin -1-rich membranes.

TL;DR: KD1-L17R was equally or more effective than aprotinin or tranexamic acid, which have been used as antifibrinolytic agents to prevent blood loss during major surgery/trauma and in a mouse liver laceration bleeding model.

TL;DR: Results highlight c‐Src activation as one of the early and pivotal mechanisms in 5‐HT2AR contractile signalling in aorta as well as supporting a role of c-Src upstream of Rho kinase.

TL;DR: TFPI-2 in platelets from normal or pregnant subjects and in plasma from pregnant women binds FV/Va and regulates intrinsic coagulation and fibrinolysis and promotes clot stabilization while attenuating intrinsic clotting.