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Yogesh Kumar
Researcher at University of California, Los Angeles
Publications - 11
Citations - 447
Yogesh Kumar is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Plasmin & Aprotinin. The author has an hindex of 6, co-authored 11 publications receiving 436 citations.
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Journal ArticleDOI
MaxiK channel partners: physiological impact
TL;DR: It is speculated that the molecular multiplicity of the C‐terminus (and intracellular loops) dictated by alternative exons may modulate or create additional interacting sites in a tissue‐specific manner.
Journal ArticleDOI
Slo1 Caveolin-binding Motif, a Mechanism of Caveolin-1-Slo1 Interaction Regulating Slo1 Surface Expression
Abderrahmane Alioua,Rong Lu,Yogesh Kumar,Mansoureh Eghbali,Pallob Kundu,Ligia Toro,Enrico Stefani +6 more
TL;DR: The results suggest 1007YNMLCFGIY1015 possible participation in Slo1 plasmalemmal targeting and demonstrate its role as a main mechanism for caveolin-1 association withSlo1 potentially serving a dual role: (i) maintaining channels in intracellular compartments downsizing their surface expression and/or (ii) serving as anchor of plasma membrane resident channels to caveolin -1-rich membranes.
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Engineering Kunitz domain 1 (KD1) of human tissue factor pathway inhibitor-2 to selectively inhibit fibrinolysis: properties of KD1-L17R variant
Madhu S. Bajaj,Godwin I. Ogueli,Yogesh Kumar,Kanagasabai Vadivel,Gregory W. Lawson,Sreejesh Shanker,Amy E. Schmidt,S. Paul Bajaj +7 more
TL;DR: KD1-L17R was equally or more effective than aprotinin or tranexamic acid, which have been used as antifibrinolytic agents to prevent blood loss during major surgery/trauma and in a mouse liver laceration bleeding model.
Journal ArticleDOI
c-Src tyrosine kinase, a critical component for 5-HT2A receptor-mediated contraction in rat aorta.
Rong Lu,Abderrahmane Alioua,Yogesh Kumar,Pallob Kundu,Mansoureh Eghbali,Noelia V. Weisstaub,Jay A. Gingrich,Enrico Stefani,Ligia Toro +8 more
TL;DR: Results highlight c‐Src activation as one of the early and pivotal mechanisms in 5‐HT2AR contractile signalling in aorta as well as supporting a role of c-Src upstream of Rho kinase.
Journal ArticleDOI
Platelets Contain Tissue Factor Pathway Inhibitor-2 Derived from Megakaryocytes and Inhibits Fibrinolysis
Kanagasabai Vadivel,Sathya-Moorthy Ponnuraj,Yogesh Kumar,Anne K. Zaiss,Matthew W. Bunce,Rodney M. Camire,Ling Wu,Denis Evseenko,Harvey R. Herschman,Madhu S. Bajaj,S. Paul Bajaj +10 more
TL;DR: TFPI-2 in platelets from normal or pregnant subjects and in plasma from pregnant women binds FV/Va and regulates intrinsic coagulation and fibrinolysis and promotes clot stabilization while attenuating intrinsic clotting.