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Yohann Bala
Researcher at BioMérieux
Publications - 36
Citations - 1851
Yohann Bala is an academic researcher from BioMérieux. The author has contributed to research in topics: Cortical bone & Bone density. The author has an hindex of 22, co-authored 35 publications receiving 1592 citations. Previous affiliations of Yohann Bala include Lyon College & French Institute of Health and Medical Research.
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Journal ArticleDOI
The role of mineralization and organic matrix in the microhardness of bone tissue from controls and osteoporotic patients
Georges Boivin,Yohann Bala,Audrey Doublier,Delphine Farlay,Louis-Georges Ste-Marie,Pierre J. Meunier,Pierre D. Delmas +6 more
TL;DR: Bone microhardness measured by Vickers indentation is an interesting methodology for the evaluation of bone strength and its determinants at the BSU level, but the organic matrix accounts for about one third of its variance.
Journal ArticleDOI
Cortical porosity identifies women with osteopenia at increased risk for forearm fractures.
Yohann Bala,Roger Zebaze,Ali Ghasem-Zadeh,Elizabeth J. Atkinson,Sandra Iuliano,James M. Peterson,Shreyasee Amin,Åshild Bjørnerem,L. Joseph Melton,Helena Johansson,John A. Kanis,Sundeep Khosla,Ego Seeman +12 more
TL;DR: In women with osteoporosis, porosity is captured by aBMD, so measuring UDR cortical porosity does not improve diagnostic sensitivity, but in womenWith osteopenia, cortex porosity was associated with forearm fractures and high porosity did not distinguish those with fractures from those without.
Journal ArticleDOI
Time sequence of secondary mineralization and microhardness in cortical and cancellous bone from ewes.
TL;DR: During the first 6 months of Mineralization, degree of mineralization and microhardness significantly increased, but then increased more slowly until at 30 months they reach their maximal values, which should be taken into account for understanding the effects of long-term treatments of bone diseases.
Journal ArticleDOI
Role of cortical bone in bone fragility.
TL;DR: It is now possible to accurately quantify cortical porosity in vivo and use this information to understand the pathogenesis of bone fragility throughout life, assist in identifying patients at risk for fracture, andUse this as a potential marker to monitor the effects of treatment on bone structure and strength.
Journal ArticleDOI
Bone micromechanical properties are compromised during long-term alendronate therapy independently of mineralization.
Yohann Bala,Yohann Bala,Baptiste Depalle,Baptiste Depalle,Delphine Farlay,Delphine Farlay,Thierry Douillard,Thierry Douillard,Sylvain Meille,Sylvain Meille,Hélène Follet,Hélène Follet,Roland Chapurlat,Roland Chapurlat,Jérôme Chevalier,Jérôme Chevalier,Georges Boivin,Georges Boivin +17 more
TL;DR: It is inferred that long‐term ALN treatment compromises micromechanical properties of the bone matrix as assessed ex vivo, and strength deficits are in part related to difference in crystallinity, irrespective of the mineral amount and mineral maturity.