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Yonatan A. Cooper
Researcher at Massachusetts Institute of Technology
Publications - 1
Citations - 82
Yonatan A. Cooper is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Epigenetics of cocaine addiction & Nucleus accumbens. The author has an hindex of 1, co-authored 1 publications receiving 62 citations.
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HDAC5 and Its Target Gene, Npas4, Function in the Nucleus Accumbens to Regulate Cocaine-Conditioned Behaviors.
Makoto Taniguchi,Maria B. Carreira,Yonatan A. Cooper,Ana-Clara Bobadilla,Jasper A. Heinsbroek,Nobuya Koike,Erin B. Larson,Evan A. Balmuth,Brandon W. Hughes,Rachel D. Penrod,Rachel D. Penrod,Jaswinder Kumar,Jaswinder Kumar,Laura N. Smith,Daniel Guzman,Joseph S. Takahashi,Tae Kyung Kim,Peter W. Kalivas,David W. Self,Yingxi Lin,Christopher W. Cowan,Christopher W. Cowan +21 more
TL;DR: It is found that dephosphorylated, nuclear histone deacetylase 5 (HDAC5) in the nucleus accumbens (NAc) reduced cocaine reward-context associations and relapse-like behaviors in a cocaine self-administration model and that nuclear HDAC5 limits reinstatement of drug seeking independent of NPAS4.