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Yong Chen

Researcher at Nanchang University

Publications -  12
Citations -  349

Yong Chen is an academic researcher from Nanchang University. The author has contributed to research in topics: Cell migration & Adhesion. The author has an hindex of 10, co-authored 12 publications receiving 304 citations.

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BMP2 promotes migration and invasion of breast cancer cells via cytoskeletal reorganization and adhesion decrease: an AFM investigation

TL;DR: The data indicated that BMP2 promoted the migration and invasion of MCF-7 cells by regulating the reorganization of cytoskeleton and the expression of adhesion molecules in/on the cells.
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Detection of erythrocytes influenced by aging and type 2 diabetes using atomic force microscope

TL;DR: The aging- and diabetes-induced changes in morphological and biomechanical properties of erythrocytes are clearly characterized at nanometer scale using atomic force microscope (AFM) to potentially be developed into a powerful tool in diagnosing diseases.
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Sonodynamic effects of hematoporphyrin monomethyl ether on CNE‐2 cells detected by atomic force microscopy

TL;DR: It was found that HMME alone had less cytotoxicity whereas HMME‐SDT could suppress the cell proliferation in a dose‐dependent manner as detected by MTT assay, and membrane toxicity and cytoskeleton disrupture induced by HMME-SDT maybe important factors to induce cell apoptosis.
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Effects of long-term serial cell passaging on cell spreading, migration, and cell-surface ultrastructures of cultured vascular endothelial cells

TL;DR: It is found that the abilities of cell spreading and migration first increased at early passages and then decreased after passage 15, in agreement with the changes in average length of actin filaments, which implies that for pre-stored adherent cells at −80 °C cell passages 5–10 are optimal for in vitro studies.
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Photoinactivation effects of hematoporphyrin monomethyl ether on Gram-positive and -negative bacteria detected by atomic force microscopy.

TL;DR: The cytotoxic and phototoxic effects of hematoporphyrin monomethyl ether (HMME) on the Gram-positive and Gram-negative bacteria were investigated, and the results indicated that there was no significant cytotoxicity but high phototoxicity in the examined concentrations.