Yongbin Zhang

TL;DR: The present work reports the first probe to image the endogenous generated SO2 without incubation of the SO2 donors and with reversible fluorescent responses toward Cys, the probe could image the enzymatic conversion of Cys to SO2 in living A549 cells in a ratiometric manner.

TL;DR: Probe Ly-NT-SP is synthesized, characterized and used for SO2 detection in lysosomes and it is confirmed that the increased SO2 can protect the small intestine against damage induced by heat shock through regulating oxidative stress in cells and mice.

TL;DR: In this work, not only were multiple binding sites constructed in the compound but also NIR fluorophores were introduced, which enables the probe to not only efficiently distinguish detection of Cys/Hcy and GSH but also achieve fluorescence imaging in vivo.

TL;DR: By intravenous injection, it revealed that the probe containing benzopyrylium ion can target tumors efficiently, and thiols are highly expressed in tumors compared to other tissues, suggesting that the tumor cure was not correlated with thiol concentration.

TL;DR: In this paper, the authors designed and obtained a near-infrared and ratiometric fluorescent probe with large stokes by reacting isophorone with coumarin, which can monitor HOCl high efficiently with quick response and low detection limit.