Caixia Yin

TL;DR: This review of recent exciting reports regarding thiol-addition reactions and their applications in thiol recognition summarizes the results and recommends a very simple and straightforward procedure for the preparation of thiolsensing probes.

TL;DR: The present work reports the first probe to image the endogenous generated SO2 without incubation of the SO2 donors and with reversible fluorescent responses toward Cys, the probe could image the enzymatic conversion of Cys to SO2 in living A549 cells in a ratiometric manner.

TL;DR: The most significant current challenges in the field of thiol-reactive probes for biomedical research and diagnostics are summarized, emphasizing the needs and opportunities that have been under-investigated by chemists in the selective probe and sensor field.

TL;DR: This review focuses on recent innovations in probe design, detection mechanisms and the investigation of biological processes and the ongoing development of fluorescent probes to enable deeper insight into the physiology of bioactive analytes.

TL;DR: A novel multi-signal fluorescent probe was rationally designed and exploited for the simultaneous detection of GSH and its metabolite SO2 via an ICT-FRET synergetic mechanism and it has been found that GSH can metabolize SO2 by enzymatic reaction with TST (thiosulphate sulphurtransferase); additionally, SO2 was transformed into sulfate under SUOX (sulfite oxidase).