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Yongtao Duan
Researcher at Boston Children's Hospital
Publications - 33
Citations - 484
Yongtao Duan is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Chemistry & Tubulin. The author has an hindex of 8, co-authored 33 publications receiving 184 citations.
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Journal ArticleDOI
A brief review on solid lipid nanoparticles: part and parcel of contemporary drug delivery systems
Yongtao Duan,Abhishek Dhar,Chetan K. Patel,Mehul Khimani,Swarnali Neogi,Prolay Sharma,Nadavala Siva Kumar,Rohit L. Vekariya +7 more
TL;DR: Although nano-structured lipid carriers and SLNs are based on lipids and surfactants, the effect of these two matrixes to build excipients is also discussed together with their pharmacological significance with novel theranostic approaches, stability and storage.
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Targeting Tubulin-colchicine Site for Cancer Therapy: Inhibitors, Antibody- Drug Conjugates and Degradation Agents
TL;DR: The present review is the first to cover a systemic and recent synopsis of tubulin-colchicine binding site agents and believes that it would provide an increase in understanding of receptor-ligand interaction pattern and consciousness of a series of challenges about tubulin target druggability.
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Triazol: a privileged scaffold for proteolysis targeting chimeras.
Li-Wen Xia,Meng-Yu Ba,Wei Liu,Weyland Cheng,Chao-Ping Hu,Qing Zhao,Yongfang Yao,Moran Sun,Yongtao Duan +8 more
TL;DR: An overview of PROTACs with a triazole scaffold is provided and its structure-activity relationship is discussed and a critical analysis of this drug discovery strategy is presented.
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Advance of promising targets and agents against COVID-19 in China.
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New Promises to Cure Cancer and Other Genetic Diseases/Disorders: Epi-drugs Through Epigenetics
TL;DR: The current article represents a review of epigenetic heritance, diseases connected with epigenetic alterations and regulatory approved epigenetic drugs as future medicines.