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Yoshiaki Manse

Researcher at Kindai University

Publications -  27
Citations -  176

Yoshiaki Manse is an academic researcher from Kindai University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 5, co-authored 15 publications receiving 94 citations.

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Melanogenesis inhibitory activity of a 7-O-9′-linked neolignan from Alpinia galanga fruit

TL;DR: An aqueous acetone extract from the fruit of Alpinia galanga demonstrated inhibitory effects on melanogenesis in theophylline-stimulated murine B16 melanoma 4A5 cells, and the active compounds 1-3 inhibited tyrosinase, tyrosine-related protein (TRP)-1, and TRP-2 mRNA expressions could be the mechanism of melanogenesis inhibitory activity.
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Acetoxybenzhydrols as highly active and stable analogues of 1'S-1'-acetoxychavicol, a potent antiallergic principal from Alpinia galanga.

TL;DR: More stable and potent analogue, 4-(methoxycarbonyloxyphenylmethyl)phenyl acetate (16), has been developed and strongly inhibited the antigen-IgE-mediated TNF-alpha and IL-4 production.
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Labdane-Type Diterpenes, Galangalditerpenes A-C, with Melanogenesis Inhibitory Activity from the Fruit of Alpinia galanga.

TL;DR: The melanogenesis inhibitory activities in theophylline-stimulated murine B16 melanoma 4A5 cells of these isolates, including the new diterpenes, were found to be more than 6–87-fold higher than that of arbutin, a commercially available positive control.
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Geranylated Coumarins From Thai Medicinal Plant Mammea siamensis With Testosterone 5α-Reductase Inhibitory Activity.

TL;DR: Geranylated coumarin constituents, kayeassamin I and mammeasins E and F, were newly isolated from the methanol extract of the flowers of Mammea siamensis and were found to inhibit testosterone 5α-reductase.
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Acylated iridoid glycosides with hyaluronidase inhibitory activity from the rhizomes of Picrorhiza kurroa Royle ex Benth.

TL;DR: Seven new acylated iridoid glycosides, picrorhizaosides A-G (1-7), were isolated from the methanol extract of the rhizomes of Picrorhiza kurroa Royle ex Benth.