Y
Yoshiharu Murata
Researcher at Nagoya University
Publications - 112
Citations - 3084
Yoshiharu Murata is an academic researcher from Nagoya University. The author has contributed to research in topics: Thyroid & Gene expression. The author has an hindex of 34, co-authored 112 publications receiving 2923 citations. Previous affiliations of Yoshiharu Murata include Memorial Hospital of South Bend.
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Increased sensitivity to thyroid hormone in mice with complete deficiency of thyroid hormone receptor α
Paolo Emidio Macchia,Yoko Takeuchi,Tomoko Kawai,Kevin Cua,Karine Gauthier,Olivier Chassande,Hisao Seo,Yoshitaka Hayashi,Jacques Samarut,Yoshiharu Murata,Roy E. Weiss,Samuel Refetoff +11 more
TL;DR: Mice completely deficient in TRalpha (TRalpha(o/o)) are produced that maintain normal serum thyroid-stimulating hormone (TSH) concentration despite low serum thyroxine (T(4), suggesting increased sensitivity to TH.
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Gap junction remodeling in hypertrophied left ventricles of aortic-banded rats: prevention by angiotensin II type 1 receptor blockade.
Luni Emdad,Mahmud Uzzaman,Yoshiko Takagishi,Haruo Honjo,Tatsuo Uchida,Nicholas J. Severs,Itsuo Kodama,Yoshiharu Murata +7 more
TL;DR: The results suggest that LV hypertrophy induced by pressure overload is associated with Cx43 gap junction disorganization and that AII may play an important role either directly or indirectly in gap-junctional remodeling.
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Tissue-specific posttranslational modification allows functional targeting of thyrotropin.
Keisuke Ikegami,Xiao Hui Liao,Yuta Hoshino,Hiroko Ono,Wataru Ota,Yuka Ito,Taeko Nishiwaki-Ohkawa,Chihiro Sato,Ken Kitajima,Masayuki Iigo,Yasufumi Shigeyoshi,Masanobu Yamada,Yoshiharu Murata,Samuel Refetoff,Takashi Yoshimura +14 more
TL;DR: Glycosylation is fundamental to a wide range of biological processes and its involvement in preventing functional crosstalk of signaling molecules in the body is demonstrated.
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Patterns of alternative splicing of fibronectin pre-mRNA in human adult and fetal tissues.
Fumitaka Oyama,Yoshiharu Murata,Nobuhiko Suganuma,Toshio Kimura,Koiti Titani,Kiyotoshi Sekiguchi +5 more
TL;DR: The results strongly suggest that the alternative splicing of fibronectin pre-mRNA in vivo is regulated in a tissue type specific manner at both the ED-A and IIICS regions and that it is developmentally regulated in liver but not in lung.
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High Incidence of Thyroid Cancer in Long-Standing Goiters with Thyroglobulin Mutations
TL;DR: The high prevalence of thyroid malignancy in patients with thyroglobulin mutations in Japan and the finding of a heterozygous activating mutation, either V599E or K600E, in cancerous tissue from each of 2 patients conclude that goiter resulting from thyrogLobulin mutation is associated with thyroid cancer.