Yoshihiko Mitsuhashi

TL;DR: The clinical features of erythroderma, trichorrhexis invaginata, and atopic manifestations were present in the majority of affected individuals and ichthyosis linearis circumflexa was seen in 12 out of 24 patients, with no clear correlation between mutations and phenotype.

TL;DR: Patients with hydroa vacciniforme (HV)‐like eruptions and malignant potential have been reported from Asia and Mexico, and those patients frequently had an associated latent Epstein–Barr virus (EBV) infection.

TL;DR: This study reports the assignment of the NS gene to chromosome 5q32, by linkage analysis and homozygosity mapping in 20 families affected with NS, and promises a better understanding of the molecular mechanisms that control epidermal differentiation and immunity.

TL;DR: Skin of patients with severe generalized recessive dystrophic epidermolysis bullosa (SGRDEB) was studied by immunoelectron microscopy and immunoblotting with antibodies to type VII collagen, a major structural component of anchoring fibrils, to suggest that a genetic defect in the correct synthesis, secretion, or in the molecular assembly oftype VII collagen may underlie S GRDEB.

TL;DR: Four risk factors for DARs were identified in the present investigation and skin reactions were observed significantly more frequently in patients for whom iotrolan was used, and 60% of these reactions were severe or moderate.