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Yoshiko Yokoyama
Researcher at Waseda University
Publications - 5
Citations - 362
Yoshiko Yokoyama is an academic researcher from Waseda University. The author has contributed to research in topics: Caspase 3 & DNA damage. The author has an hindex of 5, co-authored 5 publications receiving 343 citations.
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ER-dependent estrogenic activity of parabens assessed by proliferation of human breast cancer MCF-7 cells and expression of ERα and PR
TL;DR: Parabens have ER-dependent estrogenic activities, and their effects on the intracellular signaling pathway might be different from that of 17beta-estradiol.
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Enhancement of Apoptosis in Developing Chick Neural Retina Cells by Basic Fibroblast Growth Factor
Yoshiko Yokoyama,Satoshi Ozawa,Yousuke Seyama,Hideo Namiki,Yokichi Hayashi,Kazuhiko Kaji,Kazuhiko Shirama,Masaki Shioda,Kazutaka Kano +8 more
TL;DR: Evidence is provided that bFGF may eventually act as a lethal factor inducing apoptotic cell death during the development of the neural retina in chick embryo.
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Dihydroheptaprenyl and dihydrodecaprenyl monophosphates induce apoptosis mediated by activation of caspase-3-like protease.
TL;DR: Results interpret these results to mean that dihydroprenyl phosphates with more than seven isoprene units have apoptosis-inducing activity and that their signal is mediated by caspase-3-like activation.
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CPP32 activation during dolichyl phosphate-induced apoptosis in U937 leukemia cells
Yoshiko Yokoyama,Tomoko Okubo,Satoshi Ozawa,Fumiko Nagai,Keiko Ushiyama,Itsu Kano,Masaki Shioda,Hirotaka Kubo,Mariko Takemura,Hideo Namiki,Etsuko Yasugi,Mieko Oshima,Yousuke Seyama,Kazutaka Kano +13 more
TL;DR: The results suggest that modulation of cAMP synthesis due to the stimulation of adenylate cyclase by dolichyl phosphate plays a critical role in CPP32 activation and apoptosis.
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DNA cleavage and 8-hydroxydeoxyguanosine formation caused by tamoxifen derivatives in vitro.
Tomoko Okubo,Fumiko Nagai,Keiko Ushiyama,Yoshiko Yokoyama,Satoshi Ozawa,Kazutaka Kano,Shunnro Tomita,Hirotaka Kubo,Itsu Kano +8 more
TL;DR: Experimental data suggest that among metabolites of tamoxifen, N-desmethyltamox ifen and probably also 4-hydroxytamoxIFen cause oxidative DNA damage in which redox cycling is involved.