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Irene Oi-Lin Ng
Researcher at University of Hong Kong
Publications - 441
Citations - 33342
Irene Oi-Lin Ng is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Hepatocellular carcinoma & Cancer. The author has an hindex of 95, co-authored 414 publications receiving 29301 citations. Previous affiliations of Irene Oi-Lin Ng include National University of Singapore & Royal Free Hospital.
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Identification and characterization of tumorigenic liver cancer stem/progenitor cells.
Stephanie Ma,Kwok Wah Chan,Liang Hu,Terence Kin Wah Lee,Jana Yim–Hung Wo,Irene Oi-Lin Ng,Bo-Jian Zheng,Xin Yuan Guan +7 more
TL;DR: In this paper, the authors identify, isolate, and characterize the CSC population that drives and maintains hepatocellular carcinoma (HCC) growth and metastasis using a severe partial hepatectomy model.
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RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2
Mengnuo Chen,Lai Wei,Cheuk-Ting Law,Felice Ho-Ching Tsang,Jialing Shen,Carol Lai-Hung Cheng,Long-Hin Tsang,Daniel W.H. Ho,David Kung-Chun Chiu,Joyce Man-Fong Lee,Carmen Chak-Lui Wong,Irene Oi-Lin Ng,Chun-Ming Wong +12 more
TL;DR: Methyltransferase‐like 3 (METTL3), a major RNA N6‐adenosine methyltransferase, was significantly up‐regulated in human hepatocellular carcinoma (HCC) and multiple solid tumors and suggest an important mechanism of epigenetic alteration in liver carcinogenesis.
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Gene expression patterns in human liver cancers.
Xin Chen,Siu Tim Cheung,Samuel So,Sheung T. Fan,Christopher Barry,John P. Higgins,Kin-Man Lai,Jiafu Ji,Sandrine Dudoit,Irene Oi-Lin Ng,Matt van de Rijn,David Botstein,Patrick O. Brown +12 more
TL;DR: Using cDNA microarrays to characterize patterns of gene expression in Hepatocellular carcinoma, consistent differences between the expression patterns in HCC compared with those seen in nontumor liver tissues are found.
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MicroRNA Expression, Survival, and Response to Interferon in Liver Cancer
Junfang Ji,Jiong Shi,Jiong Shi,Anuradha Budhu,Zhipeng Yu,Marshonna Forgues,Stephanie Roessler,Stefan Ambs,Yi Chen,Paul S. Meltzer,Carlo M. Croce,Lun Xiu Qin,Kwan Man,Chung Mau Lo,Joyce Man-Fong Lee,Irene Oi-Lin Ng,Jia Fan,Zhao-You Tang,Hui-Chuan Sun,Xin Wei Wang +19 more
TL;DR: The expression patterns of microRNAs in liver tissue differ between men and women with hepatocellular carcinoma, and the miR-26 expression status of such patients is associated with survival and response to adjuvant therapy with interferon alfa.
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Improving survival results after resection of hepatocellular carcinoma: a prospective study of 377 patients over 10 years.
Ronnie T.P. Poon,Sheung Tat Fan,Chung Mau Lo,Irene Oi-Lin Ng,Chi-Leung Liu,Chi Ming Lam,John Wong +6 more
TL;DR: Significant improvement of overall and disease-free survival results after resection of HCC has been achieved within the past decade as a result of advances in the diagnosis and surgical management of H CC.