Showing papers by "Yoshitaka Fujii published in 2016"
Niigata University1, Mie University2, Kumamoto University3, Shinshu University4, Sapporo Medical University5, Teikyo University6, Kyoto University7, Kanazawa University8, Kyoto Prefectural University of Medicine9, Tenri Hospital10, Yamaguchi University11, Toho University12, Chiba University13, Fukushima Medical University14
TL;DR: Knowing the pathological diagnosis is important to determine the indications for limited resection for adenocarcinoma, and the technique should be performed with caution in squamous cell carcinoma and other pathologies.
Abstract: Objective
A precise preoperative diagnosis of in situ or minimally invasive carcinoma may identify patients who can be treated by limited resection. Although some clinical trials of limited resection for lung cancer have started, it will take a long time before the results will be published. We have already reported a large-scale study of limited resection. We herein report the data for a subclass analysis according to differences in pathology.
19 citations
TL;DR: A positive correlation between the variant GG genotype of CTSO rs10030044 and shorter disease-free survival, or overall survival in hormone receptor-positive breast cancer patients receiving adjuvant tamoxifen therapy is found.
Abstract: Background
Tamoxifen can reduce the occurrence of breast cancer by a half in high-risk women. Recently, a genome-wide association study identified two single-nucleotide polymorphisms (SNPs) near or in the CTSO and ZNF423 genes that were associated with breast cancer risk during tamoxifen therapy. We hypothesized that these two SNPs could be associated with increased recurrence in breast cancer patients who received adjuvant tamoxifen therapy.
8 citations
TL;DR: A novel simple method to secure an adequate surgical margin is suggested: the dual outline of navigating utensil in thoracoscopic segmentectomy (DONUTS) method, which was used to secure a new resection line.
Abstract: Thoracoscopic segmentectomy requires an adequate surgical margin; however, only a few reports have described the procedure of how to maintain a constant distance from the tumour. We here suggest a novel simple method to secure an adequate surgical margin: the dual outline of navigating utensil in thoracoscopic segmentectomy (DONUTS) method. We used a DONUTS indicator sheet produced from a 1.5-mm thick absorbed sheet with a proper diameter to secure an adequate surgical margin. The indicator sheet, which was affixed to the pleura, indicated a new resection line. With this new line, an additional excision was performed in addition to conventional segmentectomy. The clinical records of 9 patients who underwent treatment with the DONUTS method between August 2011 and December 2013 were retrospectively reviewed. No postoperative complications of loco-regional recurrence were observed over a mean period of 20.3 months.