Y
Young Yang
Researcher at Sookmyung Women's University
Publications - 205
Citations - 9810
Young Yang is an academic researcher from Sookmyung Women's University. The author has contributed to research in topics: Cancer & Apoptosis. The author has an hindex of 47, co-authored 190 publications receiving 8996 citations. Previous affiliations of Young Yang include Scripps Research Institute & KAIST.
Papers
More filters
Journal ArticleDOI
The roles of iron in health and disease
TL;DR: The latest progress in studies of iron metabolism and the current understanding of the molecular mechanisms of iron absorption, transport, utilization, and storage are discussed.
Journal ArticleDOI
A viral inhibitor of peptide transporters for antigen presentation
Klaus Früh,Kwangseog Ahn,Hakim Djaballah,Pascal Sempé,Peter van Endert,Robert Tampé,Per A. Peterson,Young Yang +7 more
TL;DR: It is shown that ICP47 efficiently inhibits peptide transport across the ER membrane such that nascent class I molecules fail to acquire antigenic peptides.
Journal ArticleDOI
Vitamin D3 Up-Regulated Protein 1 Mediates Oxidative Stress Via Suppressing the Thioredoxin Function
Eunsung Junn,Seung Hyun Han,Joo Young Im,Young Yang,Eun Wie Cho,Hong Duck Um,Do Kyun Kim,Kang Woo Lee,Pyung Lim Han,Sue Goo Rhee,In Pyo Choi +10 more
TL;DR: Results demonstrate that mVDUP1 functions as an oxidative stress mediator by inhibiting TRX activity.
Journal ArticleDOI
TCR-mediated internalization of peptide-MHC complexes acquired by T cells
Jing-Feng Huang,Young Yang,Homero Sepulveda,Weixing Shi,Inkyu Hwang,Per A. Peterson,Michael R. Jackson,Jonathan Sprent,Zeling Cai +8 more
TL;DR: This form of immunoregulation could explain the "exhaustion" of T cell responses that is induced by high viral loads and may serve to down-regulate immune responses.
Journal ArticleDOI
Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47.
Kwaangseog Ahn,Thomas H. Meyer,Stephan Uebel,Pascal Sempé,Hakim Djaballah,Young Yang,Per A. Peterson,Klaus Früh,Robert Tampé +8 more
TL;DR: It is demonstrated that recombinant, purified ICP47 containing a hexahistidine tag inhibits peptide import into microsomes of insect cells expressing human TAP, whereas inhibition of peptide transport by murine TAP was much less effective, suggesting an intrinsic species‐specificity of I CP47.