P
Peter van Endert
Researcher at French Institute of Health and Medical Research
Publications - 161
Citations - 12730
Peter van Endert is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: MHC class I & Antigen. The author has an hindex of 50, co-authored 147 publications receiving 11273 citations. Previous affiliations of Peter van Endert include Necker-Enfants Malades Hospital & Paris Descartes University.
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Journal ArticleDOI
Calreticulin exposure dictates the immunogenicity of cancer cell death
Michel Obeid,Antoine Tesniere,Antoine Tesniere,Antoine Tesniere,François Ghiringhelli,François Ghiringhelli,François Ghiringhelli,Gian Maria Fimia,Lionel Apetoh,Lionel Apetoh,Lionel Apetoh,Jean-Luc Perfettini,Jean-Luc Perfettini,Jean-Luc Perfettini,Maria Castedo,Maria Castedo,Maria Castedo,Grégoire Mignot,Grégoire Mignot,Grégoire Mignot,Theoharis Panaretakis,Theoharis Panaretakis,Theoharis Panaretakis,Noelia Casares,Noelia Casares,Noelia Casares,Didier Métivier,Didier Métivier,Didier Métivier,Nathanael Larochette,Nathanael Larochette,Nathanael Larochette,Peter van Endert,Peter van Endert,Fabiola Ciccosanti,Mauro Piacentini,Laurence Zitvogel,Laurence Zitvogel,Laurence Zitvogel,Guido Kroemer,Guido Kroemer,Guido Kroemer +41 more
TL;DR: It is shown that anthracyclin-induced CRT translocation induces the rapid, preapoptotic translocation of calreticulin (CRT) to the cell surface and is identified as a key feature determining anticancer immune responses.
Journal ArticleDOI
ER–phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells
Pierre Guermonprez,Loredana Saveanu,Monique J. Kleijmeer,Jean Davoust,Peter van Endert,Sebastian Amigorena +5 more
TL;DR: It is shown that soon after or during formation, phagosomes fuse with the ER, and cross-presentation in dendritic cells occurs in a specialized, self-sufficient, ER–phagosome mix compartment.
Journal ArticleDOI
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death
Theocharis Panaretakis,Theocharis Panaretakis,Theocharis Panaretakis,Oliver Kepp,Oliver Kepp,Oliver Kepp,Ulf Brockmeier,Antoine Tesniere,Antoine Tesniere,Antoine Tesniere,Ann Charlotte Björklund,Daniel C. Chapman,Michael Durchschlag,Nicholas Joza,Nicholas Joza,Nicholas Joza,Gérard Pierron,Peter van Endert,Peter van Endert,Junying Yuan,Laurence Zitvogel,Laurence Zitvogel,Frank Madeo,David B. Williams,Guido Kroemer,Guido Kroemer,Guido Kroemer +26 more
TL;DR: Depletion of PERK, caspase‐8 or SNAREs had no effect on cell death induced by anthracyclines, yet abolished the immunogenicity of cell death, which could be restored by absorbing recombinant CRT to the cell surface.
Journal ArticleDOI
A viral inhibitor of peptide transporters for antigen presentation
Klaus Früh,Kwangseog Ahn,Hakim Djaballah,Pascal Sempé,Peter van Endert,Robert Tampé,Per A. Peterson,Young Yang +7 more
TL;DR: It is shown that ICP47 efficiently inhibits peptide transport across the ER membrane such that nascent class I molecules fail to acquire antigenic peptides.
Journal ArticleDOI
Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells.
Yuting Ma,Yuting Ma,Yuting Ma,Sandy Adjemian,Sandy Adjemian,Sandy Adjemian,Stephen R. Mattarollo,Takahiro Yamazaki,Takahiro Yamazaki,Takahiro Yamazaki,Laetitia Aymeric,Laetitia Aymeric,Laetitia Aymeric,Heng Yang,João Paulo Portela Catani,Dalil Hannani,Dalil Hannani,Dalil Hannani,Helene Duret,Kim Steegh,Isabelle Martins,Isabelle Martins,Isabelle Martins,Frédéric Schlemmer,Frédéric Schlemmer,Frédéric Schlemmer,Mickaël Michaud,Mickaël Michaud,Mickaël Michaud,Oliver Kepp,Oliver Kepp,Oliver Kepp,Abdul Qader Sukkurwala,Abdul Qader Sukkurwala,Abdul Qader Sukkurwala,Laurie Menger,Laurie Menger,Laurie Menger,Erika Vacchelli,Erika Vacchelli,Erika Vacchelli,Nathalie Droin,Nathalie Droin,Lorenzo Galluzzi,Lorenzo Galluzzi,Roman Krzysiek,Siamon Gordon,Philip R. Taylor,Peter van Endert,Eric Solary,Eric Solary,Eric Solary,Mark J. Smyth,Laurence Zitvogel,Laurence Zitvogel,Laurence Zitvogel,Guido Kroemer +56 more