P
Pora Kim
Researcher at University of Texas Health Science Center at Houston
Publications - 44
Citations - 2076
Pora Kim is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Gene & Fusion gene. The author has an hindex of 18, co-authored 34 publications receiving 1426 citations. Previous affiliations of Pora Kim include Electronics and Telecommunications Research Institute & Ewha Womans University.
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Journal ArticleDOI
Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas
Theo A. Knijnenburg,Linghua Wang,Michael T. Zimmermann,Nyasha Chambwe,Galen F. Gao,Andrew D. Cherniack,Huihui Fan,Hui Shen,Gregory P. Way,Casey S. Greene,Yuexin Liu,Rehan Akbani,Bin Feng,Lawrence A. Donehower,Chase Miller,Yang Shen,Mostafa Karimi,Haoran Chen,Pora Kim,Peilin Jia,Eve Shinbrot,Shaojun Zhang,Jianfang Liu,Hai Hu,Matthew H. Bailey,Christina Yau,Denise M. Wolf,Zhongming Zhao,John N. Weinstein,Lei Li,Li Ding,Gordon B. Mills,Peter W. Laird,David A. Wheeler,Ilya Shmulevich,Raymond J. Monnat,Yonghong Xiao,Chen Wang +37 more
TL;DR: These frequent DDR gene alterations in many human cancers have functional consequences that may determine cancer progression and guide therapy and a new machine-learning-based classifier developed from gene expression data allowed to identify alterations that phenocopy deleterious TP53 mutations.
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TSGene 2.0: an updated literature-based knowledgebase for tumor suppressor genes
TL;DR: TSGene 2.0, which is the only available database for TSGs, provides the most updated TSGs and their features in pan-cancer.
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Discovery of ALK-PTPN3 gene fusion from human non-small cell lung carcinoma cell line using next generation RNA sequencing
Yeonjoo Jung,Pora Kim,Yeonhwa Jung,Juhee Keum,Soon Kim,Yong Soo Choi,In Gu Do,Jinseon Lee,So Jung Choi,Su Jin Kim,Jong Eun Lee,Jhingook Kim,Sanghyuk Lee,Jaesang Kim +13 more
TL;DR: This study confirms the utility of next generation sequencing as a tool for the discovery of somatic mutations and has led to the identification of a novel mutation in NSCLC that may be of diagnostic, prognostic, and therapeutic importance.
Journal ArticleDOI
ChimerDB 2.0—a knowledgebase for fusion genes updated
Pora Kim,Suhyeon Yoon,Namshin Kim,Sang-Hyun Lee,Minjeong Ko,Haeseung Lee,Hyun-Jung Kang,Jaesang Kim,Sanghyuk Lee +8 more
TL;DR: The algorithm of identifying fusion transcripts is more sensitive and has detected 2699 fusion transcripts with high confidence, and a new alignment viewer is developed that should facilitate examining reliability of fusion transcripts and inferring functional significance in ChimerDB 2.0.
Journal ArticleDOI
A high-dimensional, deep-sequencing study of lung adenocarcinoma in female never-smokers.
Sang Cheol Kim,Yeonjoo Jung,Jinah Park,Sooyoung Cho,Chaehwa Seo,Jaesang Kim,Pora Kim,Jehwan Park,Jihae Seo,Jihae Seo,Jiwoong Kim,Seong-Jin Park,Insu Jang,Namshin Kim,Jin Ok Yang,Byungwook Lee,Kyoohyoung Rho,Yeonhwa Jung,Juhee Keum,Jinseon Lee,Jungho Han,Sangeun Kang,Sujin Bae,So Jung Choi,Su Jin Kim,Jong Eun Lee,Wankyu Kim,Jhingook Kim,Sanghyuk Lee,Sanghyuk Lee +29 more
TL;DR: The most prominent gene network module that emerged indicates that disturbances in G2/M transition and mitotic progression are causally linked to tumorigenesis in these patients, and results from the analysis strongly suggest that several novel microRNA-target interactions represent key regulatory elements of the gene network.