Yousaf Ali

TL;DR: Azo dyes are widely used in textile, fiber, cosmetic, leather, paint and printing industries and have the ability to be used as drug carriers, either by acting as a 'cargo' that entrap therapeutic agents or by prodrug approach.

TL;DR: Docking analysis suggests that the synthesized compounds were anchored well in the catalytic site and extending to the entrance of binding pocket and thus restrict the mobility of the flap by interacting with its key amino acid residues.

TL;DR: This is the first overview briefly summarizing the prognostic feature of TOP-IIA in various types of cancer, and highlights the research output and analysis in exploring the standing of topoisomerase inhibitor in various carcinomas.

TL;DR: In this paper, a single dose of ethanol (5 g/kg body weight) was intraperitoneally administered after the birth of rat pups on PND-7, which caused oxidative stress accompanied by the activation of phosphorylated-c-Jun N-terminal kinase (p-JNK), nod-like receptor family pyrin domain containing 3 (NLRP3), apoptosis-associated speck-like protein (ASC), and cysteine-aspartic acid protease-1 (caspase-one) proteins to form

TL;DR: Prospects provide suggestions and clues for novel sophoridine-based anticancer agents with enhanced expected efficacy and minimum toxicity and the current market of anticancer drugs and its expected growth are discussed.