D
Debra Hoppensteadt
Researcher at Loyola University Chicago
Publications - 466
Citations - 7440
Debra Hoppensteadt is an academic researcher from Loyola University Chicago. The author has contributed to research in topics: Heparin & Anticoagulant. The author has an hindex of 41, co-authored 433 publications receiving 6706 citations. Previous affiliations of Debra Hoppensteadt include Aalborg Hospital & Loyola University Medical Center.
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Journal ArticleDOI
Proinflammatory cytokines in the prefrontal cortex of teenage suicide victims
Ghanshyam N. Pandey,Hooriyah S. Rizavi,Xinguo Ren,Jawed Fareed,Debra Hoppensteadt,Rosalinda C. Roberts,Robert R. Conley,Yogesh Dwivedi +7 more
TL;DR: An important role for IL-1β, IL-6, and TNF-α in the pathophysiology of suicidal behavior is suggested and that proinflammatory cytokines may be an appropriate target for developing therapeutic agents are suggested.
Journal ArticleDOI
Treatment of Severe Veno-Occlusive Disease With Defibrotide: Compassionate Use Results in Response Without Significant Toxicity in a High-Risk Population
Paul G. Richardson,Anthony D. Elias,Amrita Krishnan,Catherine Wheeler,Raj Nath,Debra Hoppensteadt,Nancy M. Kinchla,Donna Neuberg,Edmund K. Waller,Joseph H. Antin,Robert J. Soiffer,James J. Vredenburgh,Michael Lill,Ann E. Woolfrey,Scott I. Bearman,Massimo Iacobelli,Jawed Fareed,Eva C. Guinan +17 more
TL;DR: Nineteen patients who developed severe VOD after SCT were treated with DF on a compassionate-use basis and the observed response rate, survival to day +100, and absence of significant DF treatment-associated toxicity are compelling and warrant further evaluation.
Journal ArticleDOI
Pro-inflammatory biomakers in depression: Treatment with venlafaxine
John E. Piletz,Angelos Halaris,Omer Iqbal,Debra Hoppensteadt,Jawed Fareed,He Zhu,James Sinacore,C. Lindsay DeVane +7 more
TL;DR: A concave quadratic equation described the associations between plasma venlafaxine concentrations and IL1β, T NFα, TNFα, and MCP-1, suggesting that these biomarkers may have become selectively lowered in the serotonergic dose range of venl Lafaxine.
Journal ArticleDOI
An update on heparins at the beginning of the new millennium.
TL;DR: The introduction of low-molecular-weight heparins (LMWHs) represents a major advance in improving the use of heparin and the development of the oral formulation of he parin and LMWHs provides an important area that may impact on the use.
Journal ArticleDOI
Oligosaccharide mapping of low molecular weight heparins: structure and activity differences.
Robert J. Linhardt,Duraikkannu Loganathan,Ali Al-Hakim,Hui Ming Wang,Jeanine M. Walenga,Debra Hoppensteadt,Jawed Fareed +6 more
TL;DR: Both gel electrophoresis and high-pressure liquid chromatography mapping techniques showed a greater structural diversity between low molecular weight heparins than had previously been observed between similarly analyzed commercial heparin preparations.