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Yupeng Wang

Researcher at Southern Medical University

Publications -  25
Citations -  352

Yupeng Wang is an academic researcher from Southern Medical University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 8, co-authored 15 publications receiving 127 citations. Previous affiliations of Yupeng Wang include Northeast Normal University & Chinese Academy of Sciences.

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Tailoring Supramolecular Prodrug Nanoassemblies for Reactive Nitrogen Species-Potentiated Chemotherapy of Liver Cancer.

TL;DR: In this article, a supramolecular prodrug nanoassemblies (SPNA) strategy that co-delivers a nitric oxide (NO) donor and a superoxide anion (O2•-) inducing chemotherapeutic agent was reported for RNS-potentiated chemotherapy.
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Engineering Endogenous Tumor-Associated Macrophage-Targeted Biomimetic Nano-RBC to Reprogram Tumor Immunosuppressive Microenvironment for Enhanced Chemo-Immunotherapy.

TL;DR: In this paper, a hemoglobin-poly(e-caprolactone) (Hb-PCL) conjugate self-assembled biomimetic nano red blood cell (nano-RBC) system (V(Hb)) is engineered to deliver chemotherapeutic doxorubicin (DOX) and oxygen for reprogramming tumor immunosuppressive microenvironment (TIME).
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Compact Vesicles Self-Assembled from Binary Graft Copolymers with High Hydrophilic Fraction for Potential Drug/Protein Delivery

TL;DR: The cooperative self-assembly endowed the hybrid vesicles with excellent resistance to protein adsorption, prolonged blood circulation time, as well as low leakage of hydrophilic drugs/proteins, making it a promising candidate as the protein carrier.
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Asymmetric copolymer vesicles to serve as a hemoglobin vector for ischemia therapy

TL;DR: In vitro HbV stability studies reveal that the encapsulation of Hb within vesicles can greatly avoid the existence of free Hb and shows no interference with cells, especially for blood components.