Synergistic enhancement of immunological responses triggered by hyperthermia sensitive Pt NPs via NIR laser to inhibit cancer relapse and metastasis.
Jie Yu,Jie Yu,Sha Liu,Yupeng Wang,Xidong He,Xidong He,Qingfei Zhang,Yanxin Qi,Dongfang Zhou,Zhigang Xie,Zhigang Xie,Xiaoyuan Li,Xiaoyuan Li,Yubin Huang,Yubin Huang +14 more
TLDR
Pt NPs can ablate tumors through PTT, and augment the anti-tumor immune response through enhanced antigen presentation and T cells infiltration, thereby preventing tumor relapse and metastasis.About:
This article is published in Bioactive Materials.The article was published on 2022-01-01 and is currently open access. It has received 27 citations till now. The article focuses on the topics: Tumor microenvironment & Cancer research.read more
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Platinum Nanoparticles in Biomedicine: Preparation, Anti-Cancer Activity, and Drug Delivery Vehicles
Atena Abed,Maryam Derakhshan,Merat karimi,Matin Shirazinia,Maryam Mahjoubin-Tehran,M. Homayonfal,Michael R. Hamblin,Seyed Abbas Mirzaei,Hamidreza Soleimanpour,Sadegh Dehghani,F. Farzaneh Dehkordi,Hamed Mirzaei +11 more
TL;DR: The development of PtNPs as an anticancer agent is one of the most valuable approaches for cancer treatment and holds great promise, especially in the area of disease diagnosis, early detection, cellular and deep tissue imaging, drug/gene delivery, as well as multifunctional therapeutics.
Journal ArticleDOI
Engineered extracellular vesicles as intelligent nanosystems for next-generation nanomedicine.
TL;DR: This review aims to provide a new insight into the design of next-generation EV-based theranostic platforms for disease treatment by comparing the therapeutic potential of intelligent EVs to traditional nanomedicine and highlighting key advantages for their clinical application.
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Fenton/Fenton-like metal-based nanomaterials combine with oxidase for synergistic tumor therapy.
TL;DR: In this article, the authors proposed a cascade catalytic system for tumor treatment based on metal-oxidase cascade catalysts, which can not only consume tumor nutrients to produce a "starvation effect", but also provide CDT with sufficient H2O2 and a suitable acidic environment, leading to enhanced antitumor effects.
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Recent advances in luminescent metallacycles/metallacages for biomedical imaging and cancer therapy.
TL;DR: An insight is provided into the paradigm of self-assembled metallacycles/metallacages in biological applications, from mono-chemotherapeutic drugs to excellent fluorescent imaging contrast agents and multifunctional therapeutic platforms.
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Dual-sensitive dual-prodrug nanoparticles with light-controlled endo/lysosomal escape for synergistic photoactivated chemotherapy
Hongtong Lu,Hongtong Lu,Shasha He,Qingfei Zhang,Qingfei Zhang,Xiaoyuan Li,Zhigang Xie,Zhigang Xie,Wang Zigui,Yanxin Qi,Yubin Huang,Yubin Huang +11 more
TL;DR: In this article, dual-sensitive dual-prodrug nanoparticles (DDNPs) were designed for photoactivated platinum-based synergistic chemotherapy in a spatiotemporal controlled manner.
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