Y
Yuxiang Lin
Researcher at Beijing Genomics Institute
Publications - 14
Citations - 951
Yuxiang Lin is an academic researcher from Beijing Genomics Institute. The author has contributed to research in topics: Microbiome & Metagenomics. The author has an hindex of 7, co-authored 14 publications receiving 614 citations.
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Journal ArticleDOI
Assessment of the cPAS-based BGISEQ-500 platform for metagenomic sequencing
Chao Fang,Huanzi Zhong,Yuxiang Lin,Bing Chen,Mo Han,Huahui Ren,Haorong Lu,Jacob M. Luber,Min Xia,Wangsheng Li,Shayna Stein,Xun Xu,Wenwei Zhang,Radoje Drmanac,Jian Wang,Huanming Yang,Lennart Hammarström,Aleksandar Kostic,Aleksandar Kostic,Karsten Kristiansen,Junhua Li +20 more
TL;DR: The high accuracy and technical reproducibility confirm the applicability of the new high-throughput sequencing platform BGISEQ-500 for metagenomic studies, though caution is still warranted when combining meetagenomic data from different platforms.
Journal ArticleDOI
1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses.
Yuanqiang Zou,Wenbin Xue,Guangwen Luo,Ziqing Deng,Panpan Qin,Ruijin Guo,Haipeng Sun,Yan Xia,Suisha Liang,Ying Dai,Daiwei Wan,Rongrong Jiang,Lili Su,Qiang Feng,Zhuye Jie,Tongkun Guo,Zhongkui Xia,Liu Chuan,Yu Jinghong,Yuxiang Lin,Shanmei Tang,Guicheng Huo,Xun Xu,Yong Hou,Xin Liu,Jian Wang,Huanming Yang,Karsten Kristiansen,Junhua Li,Huijue Jia,Liang Xiao +30 more
TL;DR: A collection of 1,520 nonredundant, high-quality draft genomes generated from >6,000 bacteria cultivated from fecal samples of healthy humans, chosen to cover all major bacterial phyla and genera in the human gut.
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Sex- and age-related trajectories of the adult human gut microbiota shared across populations of different ethnicities
Xiuying Zhang,Huanzi Zhong,Yufeng Li,Zhun Shi,Huahui Ren,Zhe Zhang,Xianghai Zhou,Shanmei Tang,Xueyao Han,Yuxiang Lin,Fangming Yang,Dan Wang,Chao Fang,Zuodi Fu,Lianying Wang,Shida Zhu,Yong Hou,Xun Xu,Huanming Yang,Jian Wang,Karsten Kristiansen,Junhua Li,Linong Ji +22 more
TL;DR: Gut microbiota of premenopausal women exhibited higher microbial diversity and higher abundances of multiple species known to have beneficial effects on host metabolism, with the abundance of Streptococcus gordonii predicting chronological age.
Journal ArticleDOI
A novel affordable reagent for room temperature storage and transport of fecal samples for metagenomic analyses.
Mo Han,Lilan Hao,Yuxiang Lin,Fang Li,Jian Wang,Huanming Yang,Liang Xiao,Karsten Kristiansen,Huijue Jia,Junhua Li +9 more
TL;DR: A novel chemical stabilizer that allows cost-effective transportation and storage at room temperature for several days with preservation of bacterial composition is described and will facilitate sample collection even in remote area and also enable transport via normal commercial transportation routes.
Journal ArticleDOI
Assessment of fecal DNA extraction protocols for metagenomic studies.
Fangming Yang,Jihua Sun,Huainian Luo,Huahui Ren,Hongcheng Zhou,Yuxiang Lin,Mo Han,Bing Chen,Hailong Liao,Susanne Brix,Junhua Li,Huanming Yang,Karsten Kristiansen,Huanzi Zhong +13 more
TL;DR: The performance of the novel protocol MP matched that of the recommended standardized protocol Q but consumed less time, was more cost-effective, and is recommended for further large-scale human gut metagenomic studies.