Z
Z. Hong Zhou
Researcher at University of California, Los Angeles
Publications - 251
Citations - 13342
Z. Hong Zhou is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Capsid & Biology. The author has an hindex of 58, co-authored 225 publications receiving 11143 citations. Previous affiliations of Z. Hong Zhou include University of Texas Health Science Center at Houston & University of Science and Technology of China.
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Journal ArticleDOI
Single particle electron microscopy analysis of the bovine anion exchanger 1 reveals a flexible linker connecting the cytoplasmic and membrane domains.
Jiansen Jiang,Nathaniel Magilnick,Kirill Tsirulnikov,Natalia Abuladze,Ivo Atanasov,Peng Ge,Mohandas Narla,Alexander Pushkin,Z. Hong Zhou,Z. Hong Zhou,Ira Kurtz +10 more
TL;DR: A new non-denaturing method of AE1 purification from bovine erythrocyte membranes is developed and a mechanism whereby flexibility of the linker region plays a critical role in regulating red cell elasticity is proposed.
Journal ArticleDOI
3D electron microscopy reveals the variable deposition and protein dynamics of the peripheral pyruvate dehydrogenase component about the core
TL;DR: The flexibility of the complex may enhance the catalytic proficiency of this macromolecular machine by promoting the channeling of the intermediates of catalysis between the active sites.
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D-loop Dynamics and Near-Atomic-Resolution Cryo-EM Structure of Phalloidin-Bound F-Actin
Sanchaita Das,Peng Ge,Zeynep A. Oztug Durer,Elena E. Grintsevich,Z. Hong Zhou,Z. Hong Zhou,Emil Reisler +6 more
TL;DR: Using disulfide crosslinking in yeast actin D-loop mutant Q41C/V45C, light-scattering measurements, and cryoelectron microscopy reconstructions, the constraints of D- loop dynamics and its contribution to F-actin formation/stability are probed.
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Structural basis for capsid recruitment and coat formation during HSV-1 nuclear egress.
Elizabeth B Draganova,Jiayan Zhang,Jiayan Zhang,Z. Hong Zhou,Z. Hong Zhou,Ekaterina E. Heldwein +5 more
TL;DR: It is hypothesized that during nuclear budding, binding of UL25 situated at the pentagonal capsid vertices to the NEC at the INM promotes formation of NEC pentagons that would anchor the NEC coat to the capsid.
Journal ArticleDOI
IRE1 phosphatase PP2Ce regulates adaptive ER stress response in the postpartum mammary gland.
TL;DR: This study provides the first in vivo evidence that PP2Ce is an essential regulator of normal lactation, possibly involving IRE1 signaling and ER stress regulation in mammary epithelium.