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Z. Ioav Cabantchik

Researcher at Hebrew University of Jerusalem

Publications -  84
Citations -  8238

Z. Ioav Cabantchik is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Transferrin & Deferiprone. The author has an hindex of 42, co-authored 79 publications receiving 7732 citations. Previous affiliations of Z. Ioav Cabantchik include Shaare Zedek Medical Center & French Institute of Health and Medical Research.

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Journal ArticleDOI

The labile iron pool: characterization, measurement, and participation in cellular processes(1).

TL;DR: Novel methodologies for assessing cellular LIP are dealt with and recent studies in which changes in LIP and ROS levels played a determining role in cellular processes are reviewed.
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Labile plasma iron in iron overload: redox activity and susceptibility to chelation

TL;DR: Oral treatment of patients with deferiprone (L1) raised plasma NTBI due to iron mobilization but did not lead to LPI appearance, indicating that L1-chelated iron in plasma was not redox active, and oral L1 treatment eliminated LPI in patients.
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Selective iron chelation in Friedreich ataxia: biologic and clinical implications.

TL;DR: In this article, the possibility of reducing brain iron accumulation in Friedreich ataxia patients with a membrane-permeant chelator capable of shuttling chelated iron from cells to transferrin, using regimens suitable for patients with no systemic iron overload.
Journal ArticleDOI

Fluorescence analysis of the labile iron pool of mammalian cells.

TL;DR: The method provides a simple, noninvasive tool for on-line monitoring of cytosolic iron under normal and abnormal conditions of cell iron supply and for assessing the dynamics of intracellular iron in living cells.