Z
Zhen-Ning Sun
Researcher at University of Hong Kong
Publications - 8
Citations - 1013
Zhen-Ning Sun is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Peroxynitrite & Hypochlorous acid. The author has an hindex of 7, co-authored 8 publications receiving 927 citations.
Papers
More filters
Journal ArticleDOI
A highly specific BODIPY-based fluorescent probe for the detection of hypochlorous acid.
TL;DR: A fluorescent probe, HKOCl-1, has been successfully developed for the detection of hypochlorous acid on the basis of a specific reaction with p-methoxyphenol and might be used as an efficient tool for probing the roles HOCl plays in biological systems.
Journal ArticleDOI
A highly selective fluorescent probe for the detection and imaging of peroxynitrite in living cells
TL;DR: A new fluorescent probe HKGreen-1 is successfully developed, which is highly selective for the detection of peroxynitrite in living cells, which was found a specific reaction between ketone 1 and peroxyne 1 (ONOO-), rather than other reactive oxygen species and reactive nitrogen species generated in the biological system.
Journal ArticleDOI
Molecular Imaging of Peroxynitrite with HKGreen-4 in Live Cells and Tissues
Tao Peng,Nai-Kei Wong,Xingmiao Chen,Yee-Kwan Chan,Derek Hoi-Hang Ho,Zhen-Ning Sun,Jun Jacob Hu,Jiangang Shen,Hani El-Nezami,Dan Yang +9 more
TL;DR: It is demonstrated that HKGreen-4 can be efficiently employed to visualize endogenous peroxynitrite generated in Escherichia coli-challenged macrophages and in live tissues from a mouse model of atherosclerosis.
Journal ArticleDOI
BODIPY-based fluorescent probe for peroxynitrite detection and imaging in living cells.
TL;DR: This work has successfully detected peroxynitrite generated in murine macrophage cells activated by phorbol 12-myristate 13-acetate (PMA), interferon-gamma (IFN-Gamma), and lipopolysaccharide (LPS).
Book ChapterDOI
Synthetic fluorescent probes for imaging of peroxynitrite and hypochlorous acid in living cells.
TL;DR: Fluorescent probes HKGreen-1 and HKOCl-1 are developed for highly sensitive detection of peroxynitrite and hypochlorous acid and have been demonstrated to be able to discriminate corresponding reactive species from other reactive oxygen and nitrogen species (ROS and RNS) in not only chemical systems but also biological systems.