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Xingmiao Chen
Researcher at University of Hong Kong
Publications - 33
Citations - 1742
Xingmiao Chen is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Peroxynitrite & Thin film. The author has an hindex of 20, co-authored 33 publications receiving 1431 citations. Previous affiliations of Xingmiao Chen include Chinese Academy of Sciences & Nanjing University.
Papers
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Journal ArticleDOI
Molecular Imaging of Peroxynitrite with HKGreen-4 in Live Cells and Tissues
Tao Peng,Nai-Kei Wong,Xingmiao Chen,Yee-Kwan Chan,Derek Hoi-Hang Ho,Zhen-Ning Sun,Jun Jacob Hu,Jiangang Shen,Hani El-Nezami,Dan Yang +9 more
TL;DR: It is demonstrated that HKGreen-4 can be efficiently employed to visualize endogenous peroxynitrite generated in Escherichia coli-challenged macrophages and in live tissues from a mouse model of atherosclerosis.
Journal ArticleDOI
Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo.
Jun Jacob Hu,Nai-Kei Wong,Sen Ye,Xingmiao Chen,Mingyang Lu,Angela Qian Zhao,Yuhan Guo,Alvin C.H. Ma,Anskar Y.H. Leung,Jiangang Shen,Dan Yang +10 more
TL;DR: Three new O2(•-) fluorescent probes are synthesized which exhibit excellent selectivity and sensitivity over a broad range of pH, strong oxidants, and abundant reductants found in cells, which open up exciting opportunities for unmasking the roles of O2 (•-) in health and disease.
Journal ArticleDOI
Caveolin‐1 regulates nitric oxide‐mediated matrix metalloproteinases activity and blood–brain barrier permeability in focal cerebral ischemia and reperfusion injury
Yong Gu,Guo-Qing Zheng,Guo-Qing Zheng,Mingjing Xu,Yue Li,Xingmiao Chen,Wenzong Zhu,Yao Tong,Sookja K. Chung,Ke Jian Liu,Jiangang Shen +10 more
TL;DR: In this paper, the role of cavolin-1 (cav-1) in regulating blood-brain barrier (BBB) permeability is investigated in the context of cerebral ischemia-reperfusion injury.
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HKOCl-3: a fluorescent hypochlorous acid probe for live-cell and in vivo imaging and quantitative application in flow cytometry and a 96-well microplate assay
Jun Jacob Hu,Nai-Kei Wong,Mingyang Lu,Xingmiao Chen,Sen Ye,Angela Qian Zhao,Peng Gao,Richard Y.T. Kao,Jiangang Shen,Dan Yang +9 more
TL;DR: An ultra-selective and ultra-sensitive HOCI fluorescent probe HKOCl-3 for live-cell and in vivo imaging and quantitative applications is described.
Journal ArticleDOI
A rationally designed rhodamine-based fluorescent probe for molecular imaging of peroxynitrite in live cells and tissues
TL;DR: A novel fluorescent reporter HKYellow was rationally designed for the robust visualization of peroxynitrite production in live cells and tissues.