Z
Zihu Guo
Researcher at Northwest A&F University
Publications - 37
Citations - 3071
Zihu Guo is an academic researcher from Northwest A&F University. The author has contributed to research in topics: Systems pharmacology & Modern medicine. The author has an hindex of 12, co-authored 33 publications receiving 1617 citations. Previous affiliations of Zihu Guo include Beijing University of Chinese Medicine & Northwest University (China).
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Journal ArticleDOI
Systems Pharmacology Dissection of the Integrated Treatment for Cardiovascular and Gastrointestinal Disorders by Traditional Chinese Medicine
Wenjuan Zhang,Qin Tao,Zihu Guo,Yingxue Fu,Xuetong Chen,Piar Ali Shar,Mohamed Shahen,Jinglin Zhu,Jun Xue,Yaofei Bai,Ziyin Wu,Zhenzhong Wang,Wei Xiao,Yonghua Wang +13 more
TL;DR: An integrated systems pharmacology approach is presented for illustrating the molecular correlations between CVDs and GIDs and suggests a novel integrated strategy for rational drug development for complex associated diseases.
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CancerHSP: anticancer herbs database of systems pharmacology
Weiyang Tao,Bohui Li,Shuo Gao,Yaofei Bai,Piar Ali Shar,Wenjuan Zhang,Zihu Guo,Ke Sun,Yingxue Fu,Chao Huang,Chunli Zheng,Jiexin Mu,Tianli Pei,Yuan Wang,Yan Li,Yonghua Wang +15 more
TL;DR: An anticancers herbs database of systems pharmacology (CancerHSP), which records anticancer herbs related information through manual curation, will help reveal the molecular mechanisms of natural anticancer products and accelerate anticancer drug development, especially facilitate future investigations on drug repositioning and drug discovery.
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Elucidation of the Anti-Inflammatory Mechanisms of Bupleuri and Scutellariae Radix Using System Pharmacological Analyses
TL;DR: Combined application of Bupleuri Radix and Scutellariae Radix was found not only to directly inhibit the synthesis and release of inflammatory cytokines, but also to have potential therapeutic effects against inflammation-induced pain.
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Weak-binding molecules are not drugs?—toward a systematic strategy for finding effective weak-binding drugs
Wang Jinan,Zihu Guo,Yingxue Fu,Ziyin Wu,Chao Huang,Chunli Zheng,Piar Ali Shar,Zhenzhong Wang,Wei Xiao,Yonghua Wang +9 more
TL;DR: In conclusion, weak-binding drugs have real opportunities for maximum efficiency and may show reduced adverse reactions, which can offer a bright and promising future for new drug discovery.
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Clarifying of the potential mechanism of Sinisan formula for treatment of chronic hepatitis by systems pharmacology method.
Zhiming Shu,Wang He,Mohamed Shahen,Zihu Guo,Jia Shu,Tiantian Wu,Xiaoyu Bian,Akhtar Hussain Shar,Mayada R. Farag,Mahmoud Alagawany,Chaobin Liu +10 more
TL;DR: The network pharmacology based analysis demonstrated that Sinisan has multi-scale curative activity in regulating chronic hepatitis related biological processes, which provides a new potential way for modern medicine in the treatment of chronic diseases.