Z
Zong-Wan Mao
Researcher at Sun Yat-sen University
Publications - 279
Citations - 10311
Zong-Wan Mao is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Chemistry & Catalysis. The author has an hindex of 50, co-authored 251 publications receiving 7958 citations. Previous affiliations of Zong-Wan Mao include Chinese Academy of Sciences & Peking University.
Papers
More filters
Journal ArticleDOI
Cyclometalated iridium(III) complexes as lysosome-targeted photodynamic anticancer and real-time tracking agents
TL;DR: In this article, four cyclometalated iridium(III)-β-carboline complexes with pH-responsive singlet oxygen (1O2) production and lysosome-specific imaging properties have been designed and synthesized.
Journal ArticleDOI
Phosphorescent iridium(III)-bis-N-heterocyclic carbene complexes as mitochondria-targeted theranostic and photodynamic anticancer agents.
TL;DR: Mechanism studies show that these complexes exert their anticancer efficacy by initiating a cascade of events related to mitochondrial dysfunction, and display up to 3 orders of magnitude higher cytotoxicity upon irradiation at 365 nm, which is so far the highest photocytotoxic responses reported for iridium complexes.
Journal ArticleDOI
G-quadruplex DNA targeted metal complexes acting as potential anticancer drugs
TL;DR: This review will highlight the recent development of G 4-interacting metal complexes, termed G4-ligands, discussing their binding modes with G-quadruplex DNA and their potential to serve as anticancer drugs in the medical field.
Journal ArticleDOI
Insights into metalloenzyme microenvironments: biomimetic metal complexes with a functional second coordination sphere.
TL;DR: An overview of recent progress in non-covalent interactions in the second coordination sphere of metalloenzymes is provided and an introduction to native metall Koenzymes with an emphasis on thesecond coordination sphere is given.
Journal ArticleDOI
Multifunctional QD-based co-delivery of siRNA and doxorubicin to HeLa cells for reversal of multidrug resistance and real-time tracking.
Jin-Ming Li,Yuan-Yuan Wang,Yuan-Yuan Wang,Mei-Xia Zhao,Cai-Ping Tan,Yi-Qun Li,Xue-Yi Le,Liang-Nian Ji,Zong-Wan Mao,Zong-Wan Mao +9 more
TL;DR: Two CdSe/ZnSe QDs modified with β-CD coupled to L-Arg or L-His were used to simultaneously deliver doxorubicin (Dox) and siRNA targeting the MDR1 gene to reverse the multidrug resistance of HeLa cells.