Institution
Comenius University in Bratislava
Education•Bratislava, Slovakia•
About: Comenius University in Bratislava is a education organization based out in Bratislava, Slovakia. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 9911 authors who have published 20523 publications receiving 439137 citations.
Topics: Population, Large Hadron Collider, Lepton, Higgs boson, Top quark
Papers published on a yearly basis
Papers
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96 citations
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TL;DR: The notion that antifungal agents used to treat vaginitis may be contributing to the drug resistance problem by promoting cross-resistance to a range of clinically used antifundals is supported.
Abstract: Vulvovaginal candidiasis is a common mucosal infection caused by opportunistic yeasts of the Candida genus. In this study, we isolated and identified the yeast species in the vagina of patients treated in the gynecology clinic and tested in vitro activities of fluconazole and itraconazole against 227 clinical yeast isolates by the NCCLS microdilution method. C. albicans (87.6%) was the most frequently identified species followed by C. glabrata (6.2%) and C. krusei (2.2%). Almost thirteen percent of yeast strains were resistant to fluconazole and 18.5% were resistant to itraconazole. Cross-resistance analyses of C. albicans isolates revealed that fluconazole resistance and itraconazole resistance were also associated with decreased susceptibilities to other azole derivatives mainly to ketoconazole and miconazole. At the same time no cross-resistance to polyene antibiotics amphotericin B and nystatin was observed. These results support the notion that antifungal agents used to treat vaginitis may be contributing to the drug resistance problem by promoting cross-resistance to a range of clinically used antifungals.
96 citations
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TL;DR: Recent advances in the identification of key proteins involved in PIM biogenesis and the determination of the three-dimensional structures of the essential phosphatidyl-myo-inositol mannosyltransferase PimA and the lipoprotein LpqW have led to important insights into the molecular basis of this pathway.
96 citations
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TL;DR: Two galactosyl transferases can apparently account for the full biosynthesis of the cell wall galactan of mycobacteria.
Abstract: Two galactosyl transferases can apparently account for the full biosynthesis of the cell wall galactan of mycobacteria. Evidence is presented based on enzymatic incubations with purified natural and synthetic galactofuranose (Galf) acceptors that the recombinant galactofuranosyl transferase, GlfT1, from Mycobacterium smegmatis, the Mycobacterium tuberculosis Rv3782 ortholog known to be involved in the initial steps of galactan formation, harbors dual beta-(1-->4) and beta-(1-->5) Galf transferase activities and that the product of the enzyme, decaprenyl-P-P-GlcNAc-Rha-Galf-Galf, serves as a direct substrate for full polymerization catalyzed by another bifunctional Galf transferase, GlfT2, the Rv3808c enzyme.
95 citations
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TL;DR: In this article, the authors measured correlations between the elliptic or triangular flow coefficients v(m) (m = 2 or 3) and other flow harmonics v(n) (n = 2 to 5) using root S-NN = 2.76 TeV Pb + Pb collision data collected in 2010 by the ATLAS experiment at the LHC.
Abstract: Correlations between the elliptic or triangular flow coefficients v(m) (m = 2 or 3) and other flow harmonics v(n) (n = 2 to 5) are measured using root S-NN = 2.76 TeV Pb + Pb collision data collected in 2010 by the ATLAS experiment at the LHC, corresponding to an integrated luminosity of 7 mu b(-1). The v(m)-v(n) correlations aremeasured in midrapidity as a function of centrality, and, for events within the same centrality interval, as a function of event ellipticity or triangularity defined in a forward rapidity region. For events within the same centrality interval, v(3) is found to be anticorrelated with v(2) and this anticorrelation is consistent with similar anticorrelations between the corresponding eccentricities, epsilon(2) and epsilon(3). However, it is observed that v(4) increases strongly with v(2), and v(5) increases strongly with both v(2) and v(3). The trend and strength of the v(m) -v(n) correlations for n = 4 and 5 are found to disagree with epsilon(m)-epsilon(n) correlations predicted by initial-geometry models. Instead, these correlations are found to be consistent with the combined effects of a linear contribution to v(n) and a nonlinear term that is a function of v(2)(2) or of v(2)v(3), as predicted by hydrodynamic models. A simple two-component fit is used to separate these two contributions. The extracted linear and nonlinear contributions to v(4) and v(5) are found to be consistent with previously measured event-plane correlations.
95 citations
Authors
Showing all 9998 results
Name | H-index | Papers | Citations |
---|---|---|---|
Andrea Bocci | 172 | 2402 | 176461 |
Daniela Bortoletto | 143 | 1883 | 108433 |
Barry Blumenfeld | 140 | 1909 | 105694 |
Dusan Bruncko | 132 | 1042 | 84709 |
Juraj Bracinik | 128 | 955 | 73765 |
Arie Bodek | 127 | 1099 | 79019 |
Stanislav Tokár | 126 | 1091 | 80366 |
Ivan Sykora | 126 | 862 | 74543 |
Pavol Strizenec | 124 | 841 | 73741 |
Dirk Zerwas | 122 | 788 | 69229 |
Eduard Kladiva | 122 | 728 | 70821 |
Mark Kruse | 116 | 1315 | 63378 |
Roman Lysak | 108 | 978 | 50423 |
P. Stavina | 104 | 411 | 48381 |
P. Federic | 103 | 463 | 45269 |