Todd L. Lowary

TL;DR: Recent advances both in the understanding of the mechanism of UGM and in the synthesis of galactofuranose and its derivatives are highlighted in this review.

TL;DR: Synthetic glycopeptides were generated and used to demonstrate that O-GlcNAc-modified peptides can be rapidly identified in complex mixtures by HPLC-coupled electrospray mass spectrometry and to conclude that the selectivity and the sensitivity of this method will make it a powerful tool for determining the sites of O- Glc NAc modification on proteins of low abundance such as transcription factors and oncogenes.

TL;DR: In comparison to AlereLAM, FujiLAM offers superior diagnostic sensitivity, while maintaining specificity, and could transform rapid point-of-care tuberculosis diagnosis for hospital inpatients with HIV.

TL;DR: The first total syntheses of these 18- and 22-residue oligosaccharides both functionalized with an aminooctyl linker arm are reported, expected to be useful tools in probing the biosynthesis of these arabinan-containing polysaccharides.

TL;DR: Together, the results provide new insights into the tolerogenic effects of costimulatory blockade and identify DC-SIGN(+) suppressive macrophages as crucial mediators of immunological tolerance with the concomitant therapeutic implications in the clinic.