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Showing papers by "Ege University published in 2001"


Journal ArticleDOI
TL;DR: In this paper, the photodegradation capacity of photoactive oxides (TiO 2, ZnO and Fe 2 O 3 ) irradiated with a sodium lamp, direct sunlight (1 sun) and concentrated sunlight (40-50 suns) in aqueous solutions was studied.
Abstract: The decrease of fluorescence emission of phenol was studied in the presence of photoactive oxides (TiO 2 , ZnO and Fe 2 O 3 ) irradiated with a sodium lamp, direct sunlight (1 sun) and concentrated sunlight (40–50 suns) in aqueous solutions. As expected photodegradation of phenol was seen to be faster for all of the oxides irradiated by concentrated sunlight. The photodegradation capacity of titanium dioxide (TiO 2 ) is superior to that of zinc oxide (ZnO) and ferric oxide (Fe 2 O 3 ) under a sodium lamp and direct sunlight, but ZnO is found to be as reactive as TiO 2 under concentrated sunlight. It has been shown that ZnO is a low cost alternative solar photocatalyst to TiO 2 for degradation of organics in aqueous solutions.

282 citations


Journal ArticleDOI
TL;DR: The data obtained show that Spirulina contains unusually high levels of gamma-linolenic acid, an essential polyunsaturated fatty acid, which is likely to benefit human health and enhance performance.
Abstract: Two New Age foods which contain high concentrations of whole food nutrients are the single-celled microalgae Chlorella and Spirulina. They are accepted as functional foods, which are defined as products derived from natural sources, whose consumption is likely to benefit human health and enhance performance. These foods are used as a supplement/ingredient or as a complete food to enhance the performance and state of the human body, or improve a specific bodily function. Functional foods are used mainly as products to nourish the human body after physical exertion or as a preventive measure against ailments. We determined the fatty acid compositions, particularly polyunsaturated fatty acid compositions, of Chlorella and Spirulina by capillary column-gas chromatography. The data obtained show that Spirulina contains unusually high levels of gamma-linolenic acid, an essential polyunsaturated fatty acid.

237 citations


Journal ArticleDOI
TL;DR: In this article, total phenols were analyzed according to the Folin-Ciocalteu method and antioxidant activities of these compounds in aqueous phase were assessed by measuring their direct ABTS.- radical scavenging abilities.
Abstract: This study was designed to determine the total phenols (TP) and total antioxidant activity (TAA) of some liquid and solid plant foods that are commonly consumed in Turkey. Total phenols were analysed according to the Folin-Ciocalteu method and antioxidant activities of these compounds in aqueous phase were assessed by measuring their direct ABTS.- radical scavenging abilities. Total phenols varied from 68 to 4162 mg/l for liquid foods and from 735 to 3994 mg/kg for solid foods. TAA of liquid and solid foods ranged between 0.61-6.78 mM and 0.63-8.62 mM, respectively. Total antioxidant activities of foods were well correlated with total phenols (r2 = 0.95). According to content of total phenols per serving, liquid foods were in the order of black tea > instant coffee > coke > red wine > violet carrot juice > apricot nectar > Turkish coffee > grape molasses > sage > white wine > linden flower, and solid foods were in the order of red grape > raisins > tarhana > dried black plum > dried apricot > grape > fresh paprika > fresh black plum > Urtica sp. > cherry > fresh apricot > paprika pickle > paprika paste.

220 citations


Journal ArticleDOI
TL;DR: Findings show that normal BP can be achieved by severe salt restriction combined with increased UF in the majority of CAPD patients, but also by a decrease in residual renal function and Kt/V index.

204 citations


Journal ArticleDOI
TL;DR: Meat pigment evolution was assessed by the spectrophotometric indexes and it was established that b* and h* CIELAB co-ordinates are the most discriminant variables.

202 citations


Journal ArticleDOI
R. N. Sener1
TL;DR: Apparent diffusion coefficient (ADC) values in the normal brain parenchyma, and those in a variety of lesions were studied by echo-planar diffusion MRI in 310 cases, and brain disorders were classified based on their ADC values.

195 citations


Journal ArticleDOI
TL;DR: In this article, the interaction of double stranded DNA (dsDNA) and single strand DNA (ssDNA) with Ru(II) complex with 2,2′-bipyridine ligand (Ru(bpy)3]2+) and methylene blue (MB) was explored by using voltammetric and spectrophotometric methods.
Abstract: The interaction of double stranded DNA (dsDNA) and single stranded DNA (ssDNA) with Ru(II) complex with 2,2′-bipyridine ligand (Ru(bpy)3]2+) and methylene blue (MB) were explored by using voltammetric and spectrophotometric methods. The electrochemistry of [Ru(bpy)3]2+ and MB was also investigated at a dsDNA-modified carbon paste electrode (CPE), a ssDNA-modified CPE and a bare CPE by means of differential pulse voltammetry (DPV), and cyclic voltammetry (CV) and the increased peak currents were observed, in respect to the order of electrodes. The structure of DNA was determined by the magnitudes of the voltammetric peaks of [Ru(bpy)3]2+ and MB. The hypochromicity of the visible absorption bands of [Ru(bpy)3]2+ and MB upon the interaction with dsDNA and ssDNA was observed. Numerous factors affecting the DNA immobilization, indicator binding reactions and ionic strength were optimized to maximize the sensitivity and reduce the assay time.

189 citations


Journal ArticleDOI
TL;DR: This is the first clinicopathological report of optic opacification occurring with this hydrophilic acrylic IOL model and studies of similar cases with this lens should be done to determine the incidence and possible mechanisms of the phenomenon.
Abstract: Purpose: To report clinical, pathological, histochemical, ultrastructural, and spectrographic analyses of explanted hydrophilic acrylic intraocular lenses (IOLs) obtained from patients who had visual disturbances caused by postoperative opacification of the lens optic. Setting: Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA, and Ege University, Alsancak Izmir, Turkey. Methods: Nine hydrophilic IOLs (SC60B-OUV, MDR Inc.) were explanted from 9 patients with decreased visual acuity. Most patients became symptomatic approximately 24 months after uneventful phacoemulsification and IOL implantation. Opacification was noted and appeared clinically to be associated with a fine granularity within the substance of the IOL optic. The IOLs were forwarded to the center and examined by gross and light microscopy. Full-thickness cut sections of the optics were stained with 1% alizarin red and the von Kossa method (special stains for calcium). Some were submitted for scanning electron microscopy and energy dispersive x-ray spectroscopy. Results: Microscopic analyses revealed multiple fine, granular deposits of variable sizes within the lens optics, usually distributed in a line parallel to the anterior and posterior curvatures of the optic, with a clear zone just beneath the optic surface. The deposits stained positive with alizarin red and the von Kossa method. Energy dispersive x-ray spectroscopy of the internal substance of sectioned IOLs demonstrated the presence of calcium within the deposits. Conclusion: This is the first clinicopathological report of optic opacification occurring with this hydrophilic acrylic IOL model. Studies of similar cases with this lens should be done to determine the incidence and possible mechanisms of the phenomenon.

163 citations


Journal ArticleDOI
TL;DR: Enhanced catalase/SOD and catal enzyme /PON ratios that are correlated with HbA1c levels are observed in diabetic patients; thus, these ratios may be used as markers of poor glycemic control and as risk factors in the development of diabetic complications.

161 citations


Journal ArticleDOI
TL;DR: Cognitive functions in patients with bilateral paramedian infarction did not change significantly during the follow‐up, in contrast to those with infarcts in varied arterial territories, allowing diagnosis before radiological examination.
Abstract: To determine clinical, behavioral, topographic and etiological patterns in patients with simultaneous bilateral thalamic infarction in varied thalamic artery territories, we studied 16 patients who were admitted to our stroke unit over a 7-year period. Patients with bithalamic infarction represented 0.6% of our registry which included 2,750 ischaemic stroke patients. On computed tomography and magnetic resonance imaging with gadolinium enhancement, there were 4 topographic patterns of infarction: 1) bilateral infarcts in the territory of paramedian artery (8 patients [50%]); 2) bilateral infarcts in the territory of thalamogeniculate arteries (3 patients [19%]); 3) bilateral infarcts involving territory of paramedian and thalamogeniculate arteries (3 patients [19%]); 4) bilateral infarcts involving territory of polar and thalamogeniculate arteries (2 patients [13%]). A specific clinical picture was found in up to 50% of the patients with bithalamic infarction. This included patients with bilateral paramedian infarction having disorder of consciousness, memory dysfunctions, various types of vertical gaze palsy and psychic changes. Bilateral sensory loss predicted accurately bilateral infarction in the territory of thalamogeniculate arteries. The main cause of bilateral thalamic infarction was small artery-disease, followed by cardioembolism. Cognitive functions in patients with bilateral paramedian infarction did not change significantly during the follow-up, in contrast to those with infarcts in varied arterial territories. Acute bilateral infarction involving both thalamus is uncommon, although they are often associated with specific neurologic-neuropsychological patterns, allowing diagnosis before radiological examination.

152 citations


Journal ArticleDOI
William Koven, S. Kolkovski, E Hadas, Kutsal Gamsız1, A. Tandler 
TL;DR: It is suggested that mobilizing the native endocrine factors associated with the feeding and digestive processes could improve MD performance in gilthead seabream and other species by maximizing its utilization.

Journal ArticleDOI
01 Sep 2001-Stroke
TL;DR: Although in Wallenberg’s syndrome the lesion due to LMI is unilateral, its effect on oropharyngeal swallowing is bilateral, and a disruption and/or disconnection of their linkage to swallowing-related cranial motor neuron pools bilaterally and to the contralateral nucleus ambiguus could produce the swallowing disorders in WS.
Abstract: Background and Purpose— We have investigated the pathophysiological mechanisms of dysphagia in Wallenberg’s syndrome (WS) that are due to lateral medullary infarction (LMI). Methods— Twenty patients with WS were evaluated by means of clinical and electrophysiological methods that measured the oropharyngeal phase of voluntarily initiated swallowing. For comparison, 22 patients with unilateral hemispheric infarction were investigated during the acute stage of stroke, and 4 patients with unilateral peripheral 9th and 10th cranial nerve palsies were studied. Age-matched 30 healthy control subjects were also included in the study. Results— It was found that dysphagia was clinically more severe in WS patients than in the patients in the other groups. The pharyngeal phase of swallowing was predominantly impaired, whereas in patients with hemispheric stroke, dysphagia was related only to the delay of triggering of the voluntarily induced swallowing. In WS patients, the swallowing reflex was extremely slow in spit...

Journal ArticleDOI
TL;DR: The data show that diabetes does not affect the presenting features of pulmonary tuberculosis to a large extent and is only associated with lower lung field disease in older patients.
Abstract: Background: Diabetes mellitus has been reported to modify the presenting features of pulmonary tuberculosis, but there are varying data, particularly regarding the association with

Journal ArticleDOI
Zeki Topcu1
TL;DR: This review highlights topoisomerase‐targeting drugs that have shown promising anticancer activities and the mechanisms by which those drugs interfere with the catalytic cycles of type I and type II DNA topoisomersases.
Abstract: DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth. Over the past few years there has been considerable pharmacological interest in these enzymes because inhibitors of DNA topoisomerases represent a major class of anticancer drugs. This review highlights topoisomerase-targeting drugs that have shown promising anticancer activities. The mechanisms by which those drugs interfere with the catalytic cycles of type I and type II DNA topoisomerases and the factors involved in the development of resistance to these drugs are discussed.

Journal ArticleDOI
TL;DR: In this paper, the interaction of epirubicin (EPR) with double-stranded DNA (dsDNA) and calf thymus single strand-linked DNA (ssDNA) at carbon paste electrode (CPE) was studied electrochemically by using differential pulse voltammetry (DPV) and cyclic voltage-amplification (CV) at CPE.

Journal ArticleDOI
TL;DR: Activity of SOD increased by the effect of drought treatments in the leaves of drought-resistant varieties TOKAK-157/37 and 56000/MISC-233 as compared to sensitive variety ERGINEL-90, and POX activity did not change throughout drought period.
Abstract: The effects of water deficit on relative water content (RWC), on the activity superoxide dismutase (SOD) and peroxidase (POX) from leaves of two drought-resistant barley strains (Hordeum vulgare L.) varieties (TOKAK-157/37 and 56000/MISC-233) and one sensitive (ERGINEL-90) were studied.

Journal ArticleDOI
TL;DR: A spectrum of imaging findings is associated with fat necrosis, and knowledge of the mammographic and US appearance and evolution of these patterns may enable imaging follow-up of these lesions, reducing the number of unnecessary biopsies.

Journal ArticleDOI
Coşkun Özcan1, Ahmet Çelik1, Zeliha Ural1, Ali Veral1, Gulsen Kandiloglu1, E. Balik1 
TL;DR: A 13-month-old boy with primary pulmonary rhabdomyosarcoma that originated within a congenital cystic adenomatoid malformation is described, which is the youngest patient of all primary pulmonary RMS cases reported in the English-language literature.

Journal ArticleDOI
TL;DR: Management procedures used in this study improved food conversion and lowered mortality without affecting body weight and rectal temperatures of the treated groups were similar to those of the controls.
Abstract: 1. This study investigated effects of conditioning at 5 d of age and food restriction during a hot period on responses to prolonged heat stress of two fast (G1 and G2) and one slower-growing (G3) broiler stocks. 2. Chicks from each stock were divided into 3 groups: control, conditioned (chicks exposed to 36 degrees C for 24 h at 5 d of age) and food restricted (during the heat stress food was withdrawn 2 h before the hot period and chicks were fed between 17.00 and 08.00 h). Prolonged heat stress was induced daily from 28 to 49 d by heating until the ambient temperature reached 32 degrees to 35 degrees C between 10.00 and 17.00 h. 3. Body weights, mortality and rectal temperatures were lower and food conversion higher for stock G3 than G1 or G2. 4. Management procedures used in this study improved food conversion and lowered mortality without affecting body weight. Rectal temperatures of the treated groups were similar to those of the controls.

Journal ArticleDOI
TL;DR: In this article, the isosteric heat of desorption and adsorption of water were determined from the equilibrium data at different temperatures using the Clasius-Clapeyron equation.

Journal ArticleDOI
TL;DR: The essential oil of Salvia tomentosa aerial parts remarkably inhibited the growth of tested Gram-positive and Gram-negative bacteria except for Pseudomonas aeruginosa.

Journal ArticleDOI
TL;DR: An HPLC method permitting the first simultaneous detection of 5 marker compounds of R. rosea offers efficient and reliable means for the evaluation of the plant material and commercial products.
Abstract: An HPLC method permitting the first simultaneous detection of 5 marker compounds (salidroside, rosarin, rosavin, rosin, rosiridin) of R. rosea was developed. A separation was achieved within 27 min by using C-18 column material, a phosphate buffer/acetonitrile gradient system and at a separation temperature of 60 degrees C. All five compounds could be detected at concentrations as low as 0.62 microg/ml and were clearly assignable in R. rosea plant material and commercial products. Therefore, this quantitative and qualitative applicability of the method offers efficient and reliable means for the evaluation of R. rosea and products thereof.

Journal ArticleDOI
TL;DR: By inhibiting the production of TGFβ1, enalapril can preserve peritoneal histology,peritoneal function, and remodeling of mesothelial cells in a rat model of experimental PF.
Abstract: ObjectivePeritoneal fibrosis (PF) is one of the most serious causes of failure in continuous ambulatory peritoneal dialysis (PD). Although the underlying mechanism responsible for the genesis of PF...

Journal ArticleDOI
R. N. Sener1
TL;DR: Diffusion imaging appears to be a promising sequence to monitor the changes in the brain tissue in herpes encephalitis, and in other infections as well with respect to restriction of movement or relatively high-motion of water molecules, providing data on the severity of the disease.

Journal ArticleDOI
TL;DR: Tetrakis as mentioned in this paper used NMe2 functionality on the carbene ligand of 1 to give the corresponding salt, 1′; whereas the reaction of 2 with HCl gave a hygroscopic and ill-defined rhodium species, which was recovered by simple phase separation and the catalytic reaction was maintained for five different runs.

Journal ArticleDOI
TL;DR: In this paper, the authors investigated the present status, the technical potentials, and the regional distribution of renewable energy resources in Turkey, taking into account solar energy, wind energy, hydro energy, geothermal energy, biomass, and wave energy.
Abstract: The effects on global and environmental air quality of pollutants released into the atmosphere from fossil fuels in power plants provide strong arguments for the development of renewable energy resources. In this regard, the objective of this study is to investigate the present status, the technical potentials, and the regional distribution of renewable energy resources in Turkey. The following resources were taken into consideration: solar energy, wind energy, hydro energy, geothermal energy, biomass, and wave energy. The present study shows that Turkey has extensive renewable energy resources that can be developed as a significant source of energy.

Journal ArticleDOI
TL;DR: It was suggested that the triggering of voluntarily induced swallows commences more than 100 ms before the onset of swallowing reflex and that this mechanism is under the control of corticobulbar–pyramidal pathways.
Abstract: The electrophysiological features of voluntarily induced and reflexive/spontaneous swallows were investigated. In normal subjects, swallows were elicited by infusing water either into the mouth (1-3 ml) or directly into the oropharyngeal region through a nasopharyngeal cannula (0.3-1 ml). For water infused orally, subjects were either requested to swallow voluntarily or instructed to resist swallowing and maintain the horizontal head position until swallowing occurred reflexively. Spontaneous saliva swallowing was investigated in patients with severe dysphagia who had a prominent clinical picture of suprabulbar palsy. Comparisons between different swallowing types were made by measuring the time interval between the onset of submental electromyographic activity (SM-EMG) and the onset of the upward movement of the larynx recorded by a movement sensor. This interval was less than 100 ms, even frequently less than 50 ms, in reflexive/spontaneous swallows, while in voluntarily induced swallows it was substantially longer. The rising time of submental muscle's excitation was also shorter in reflexive/spontaneous swallows. It was suggested that the triggering of voluntarily induced swallows commences more than 100 ms before the onset of swallowing reflex and that this mechanism is under the control of corticobulbar-pyramidal pathways. If the swallowing reflex is triggered within such a short period of time following the onset of SM-EMG, the central control by the bulbar swallowing center should be effective until the end of oropharyngeal swallowing.

Journal ArticleDOI
TL;DR: Eleven of the most promising Sarilop clones and one clone of Sarizeybek, all selected from a former agronomic evaluation, were analysed by three molecular marker techniques, isozymes, RAPDs and AFLPs and the resolution power and the accuracy of these three analytical techniques, in distinguishing among fig clones were determined.

Journal ArticleDOI
TL;DR: The electrophysiologic method of measuring dysphagia limit confirms neurogenic dysphagIA and its severity in the neutral head position and changes in head and neck postures do not significantly alter dysphagio limit in unimpaired subjects except for the chin-up position.

Journal ArticleDOI
TL;DR: In this paper, the existence of positive solutions of second-order nonlinear differential equations on a finite interval with periodic boundary conditions was proved and upper and lower bounds for these positive solutions were given.