Government College of Science

About: Government College of Science is a education organization based out in Lahore, Pakistan. It is known for research contribution in the topics: Thin film & Triboluminescence. The organization has 90 authors who have published 105 publications receiving 769 citations.

Synthesis of Zn(II) 5,10,15,20-tetrakis(4′-isopropylphenyl) porphyrin and its use as a thin film sensor

Abstract: In this paper, we have reported the synthesis and use of an organic semiconductor Zn(II) 5,10,15,20-tetrakis(4′-isopropylphenyl) porphyrin (ZnTIPP) as an active material in a surface type sensor. Ag/ZnTIPP/Ag sensor was fabricated by thermal sublimation of ZnTIPP on a glass substrate with preliminary deposited surface type silver electrodes. Semiconducting channel between silver electrodes was 0.04 mm × 15 mm. Changes in electrical measurements of the device were observed with increase of relative humidity, illumination, and temperature. A small degree of hysteresis and acceptable response and recovery times were observed over a wide range of relative humidity. Activation energy of the ZnTIPP was estimated.

A panoramic spectrum of complex interplay between the immune system and IL-32 during pathogenesis of various systemic infections and inflammation

Abstract: Cytokines have always been of great interest due to their vast potential and participation in the progression and pathogenesis of various ailments. Interleukin-32 (IL-32) is a recently identified cytokine, whose gene is located on human chromosome 16 p13.3, with eight exons and six splice variants (IL-32α to IL-32ζ). IL-32α, the most abundant form, is secreted by different types of cells including T cells, natural killer (NK) cells, monocytes, endothelial cells and epithelial cells. It acts as a preferential mediator and effector of abnormal immune responses to multiple inflammatory and auto immune diseases including rheumatoid arthritis, chronic obstructive pulmonary disease (COPD), inflammatory bowel disease (IBD), etc. It was found to stimulate the induction of various chemokines, pro-inflammatory cytokines including IL-1β, IL-6, IL-8, TNF-α and macrophage inflammatory protein-2 (MIP-2). Hence, IL-32 mediates the crucial interplay among immune system and body cells during pathogenesis of various insults. The aim of the present effort is to summarize the role, mechanism of pathogenesis and potential therapeutic applications of IL-32 in different systemic infections and diseased conditions.

Cu(II) 5,10,15,20-tetrakis(4′-isopropylphenyl) porphyrin based surface-type resistive–capacitive multifunctional sensor

Abstract: An organic semiconductor Cu(II) 5,10,15,20-tetrakis(4′-isopropylphenyl) porphyrin (CuTIPP) was synthesized and investigated as an active material in resistive–capacitive multifunctional sensor. A thin film of the CuTIPP was deposited by thermal evaporator on a glass substrate with preliminary deposited silver electrodes and Ag/CuTIPP/Ag surface-type multifunctional sensor was fabricated. Thickness of the CuTIPP film was 100 nm. Area of the semiconducting channel between metallic electrodes was 40 μm × 21 mm. A change in electrical resistance and capacitance was observed with the increase of temperature, relative humidity and illumination. An equivalent circuit of the Ag/CuTIPP/Ag capacitive–resistive humidity, temperature and illumination sensor was developed. Humidity, temperature and illumination dependent capacitance–resistance properties of this sensor make it beneficial for use in humidity, temperature and lux multimeters.

Potential of 5,10,15,20-Tetrakis(3′,5′-di-tertbutylphenyl)porphyrinatocopper(II) for a multifunctional sensor

Abstract: An organic compound 5,10,15,20-Tetrakis(3′,5′-di-tertbutylphenyl)porphyrinatocopper(II) (TDTPPCu) is synthesized and studied as an active material for multifunctional capacitive sensor. The capacitance of the device as a function of illumination, humidity and temperature has been investigated. It is observed that the capacitance increases by 4.7 times from the dark condition under an illumination of 3850 lx. The capacitance is also changed 9.5 times with the increase in relative humidity (RH) from 30% to 95%. No change in capacitance appeared below critical temperature 120 °C. Based on the experimental results for the multifunctional sensor a mathematical model has been developed. The model is mainly based on the assumption that the capacitive response of the sensor is associated with dielectric polarization. The sensors are simulated using this model. The simulated results match well with experimental results.