Institution
Government of the District of Columbia
Government•Washington D.C., District of Columbia, United States•
About: Government of the District of Columbia is a government organization based out in Washington D.C., District of Columbia, United States. It is known for research contribution in the topics: Health care & Poison control. The organization has 74 authors who have published 56 publications receiving 1067 citations. The organization is also known as: government of Washington, D.C. & Washington, DC government.
Topics: Health care, Poison control, Population, Public health, Acquired immunodeficiency syndrome (AIDS)
Papers published on a yearly basis
Papers
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TL;DR: Clinicians have an urgent need for prompt communication of vital epidemiologic information that could focus their diagnostic evaluation, and rapid diagnostic assays to distinguish more common infectious processes from agents of bioterrorism also could improve management strategies.
Abstract: On October 9, 2001, a letter containing anthrax spores was mailed from
New Jersey to Washington, DC. The letter was processed at a major postal facility
in Washington, DC, and opened in the Senate's Hart Office Building on October
15. Between October 19 and October 26, there were 5 cases of inhalational
anthrax among postal workers who were employed at that major facility or who
handled bulk mail originating from that facility. The cases of 2 postal workers
who died of inhalational anthrax are reported here. Both patients had nonspecific
prodromal illnesses. One patient developed predominantly gastrointestinal
symptoms, including nausea, vomiting, and abdominal pain. The other patient
had a "flulike" illness associated with myalgias and malaise. Both patients
ultimately developed dyspnea, retrosternal chest pressure, and respiratory
failure requiring mechanical ventilation. Leukocytosis and hemoconcentration
were noted in both cases prior to death. Both patients had evidence of mediastinitis
and extensive pulmonary infiltrates late in their course of illness. The durations
of illness were 7 days and 5 days from onset of symptoms to death; both patients
died within 24 hours of hospitalization. Without a clinician's high index
of suspicion, the diagnosis of inhalational anthrax is difficult during nonspecific
prodromal illness. Clinicians have an urgent need for prompt communication
of vital epidemiologic information that could focus their diagnostic evaluation.
Rapid diagnostic assays to distinguish more common infectious processes from
agents of bioterrorism also could improve management strategies.
174 citations
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TL;DR: Results from the first national-level analysis of transgender people with diagnosed HIV infection are presented, indicating improvements in data collection methods and quality are needed to gain a better understanding of HIV burden among transgender people.
Abstract: Publications on diagnosed HIV infection among transgender people have been limited to state- or local-level data. We analyzed data from the National HIV Surveillance System and present results from the first national-level analysis of transgender people with diagnosed HIV infection. From 2009 to 2014, HIV surveillance jurisdictions from 45 states plus the District of Columbia identified and reported at least one case of newly diagnosed HIV infection for transgender people; jurisdictions from 5 states reported no cases for transgender people. Of 2351 transgender people with newly diagnosed HIV infection during 2009–2014, 84.0% were transgender women (male-to-female), 15.4% were transgender men (female-to-male), and 0.7% were additional gender identity (e.g., gender queer, bi-gender). Over half of both transgender women (50.8%; 1002/1974) and men (58.4%; 211/361) with newly diagnosed HIV infection were non-Hispanic black/African American. Improvements in data collection methods and quality are needed to gain a better understanding of HIV burden among transgender people.
152 citations
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TL;DR: In this paper, the authors examined whether the incorporation of remotely sensed and spatially distributed datasets can improve the overall performance of the hydrological model and found that the performance of this model was improved using both calibration techniques by achieving Nash-Sutcliffe efficiency (NSE) values < 0.5 (0.73-0.85).
111 citations
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TL;DR: Aerosolization of the thermophilous fungal opportunist Aspergillus fumigatus from mechanically agitated compost piles was examined at a pilot-scale sewage sludge composting facility and two selected test sites.
Abstract: Aerosolization of the thermophilous fungal opportunist Aspergillus fumigatus from mechanically agitated compost piles was examined at a pilot-scale sewage sludge composting facility and two other selected test sites. Aerosols of A. fumigatus downwind from stationary compost piles were insignificant in comparison with those downwind from agitated piles. These aerosols were generated by a front-end loader moving and dropping compost. Aerial concentrations of the fungus at distances downwind from the point of emission were used to determine an emission rate for A. fumigatus associated with the moving operations. The maximum emission rate, 4.6 × 106A. fumigatus particles per s, was used to calculate predicted concentrations in an unobstructed plume with restrictive, neutral, and dispersive atmospheric mixing conditions up to 1 km downwind from the emission source.
89 citations
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TL;DR: There was no evidence of substitution to other antipsychotics, and 9-month mortality and hospital use were similar between the treatment vs control arms, and the study followed outcomes to 2 years.
Abstract: Importance Antipsychotic agents, such as quetiapine fumarate, are frequently overprescribed for indications not supported by clinical evidence, potentially causing harm. Objective To investigate if peer comparison letters targeting high-volume primary care prescribers of quetiapine meaningfully reduce their prescribing. Design, Setting, and Participants Randomized clinical trial (intent to treat) conducted from 2015 to 2017 of prescribers and their patients nationwide in the Medicare program. The trial targeted the 5055 highest-volume primary care prescribers of quetiapine in 2013 and 2014 (approximately 5% of all primary care prescribers of quetiapine). Interventions Prescribers were randomized (1:1 ratio) to receive a placebo letter or 3 peer comparison letters stating that their quetiapine prescribing was high relative to their peers and was under review by Medicare. Main Outcomes and Measures The primary outcome was the total quetiapine days supplied by prescribers from the intervention start to 9 months. Secondary outcomes included quetiapine receipt from all prescribers by baseline patients, quetiapine receipt by patients with low-value or guideline-concordant indications for therapy, mortality, and hospital use. In exploratory analyses, the study followed outcomes to 2 years. Results Of the 5055 prescribers, 231 (4.6%) were general practitioners, 2428 (48.0%) were in family medicine, and 2396 (47.4%) were in internal medicine; 4155 (82.2%) were male. All were included in the analyses. Over 9 months, the treatment arm supplied 11.1% fewer quetiapine days per prescriber vs the control arm (2456 vs 2864 days; percentage difference, 11.1% fewer days; 95% CI, −13.1% to −9.2% days;P Conclusions and Relevance Peer comparison letters caused substantial and durable reductions in quetiapine prescribing, with no evidence of negative effects on patients. Trial Registration ClinicalTrials.gov identifier:NCT02467933
67 citations
Authors
Showing all 74 results
Name | H-index | Papers | Citations |
---|---|---|---|
Erin Holve | 16 | 46 | 1238 |
Jenevieve Opoku | 12 | 31 | 574 |
Amirreza Sharifi | 11 | 19 | 329 |
Michael Kharfen | 11 | 34 | 440 |
Yujiang Jia | 7 | 11 | 266 |
Tiffany West | 7 | 11 | 217 |
Charles R. Hayman | 6 | 14 | 177 |
Lynette Stokes | 5 | 5 | 297 |
David Yokum | 3 | 4 | 164 |
Adam Allston | 3 | 12 | 41 |
J. L. Luke | 3 | 4 | 94 |
Charlene Lanza | 3 | 3 | 132 |
Martin E. Levy | 3 | 3 | 264 |
Brittani Saafir-Callaway | 3 | 4 | 26 |
R. L. DuPont | 3 | 3 | 77 |