Istituto Universitario Di Studi Superiori Di Pavia

About: Istituto Universitario Di Studi Superiori Di Pavia is a education organization based out in Pavia, Italy. It is known for research contribution in the topics: Pulsar & Neutron star. The organization has 162 authors who have published 566 publications receiving 22605 citations.

Model of seismic design lateral force levels for the existing reinforced concrete European building stock

Abstract: As part of the development of a European Seismic Risk Model 2020 (ESRM20), the spatial and temporal evolution of seismic design across Europe has been studied in order to better classify reinforced concrete buildings (which represent more than 30% of the approximately 145 million residential, commercial and industrial buildings in Europe) and map them to vulnerability models based on simulated seismic design. This paper summarises the model that has been developed to assign the years when different seismic design levels (low code, moderate code and high code) were introduced in a number of European countries and the associated lateral forces that were specified spatially within each country for the low and moderate codes for typical reinforced concrete mid-rise buildings. This process has led to an improved understanding of how design regulations evolved across Europe and how this has impacted the vulnerability of the European residential building stock. The model estimates that ~ 60% of the reinforced concrete buildings in Europe have been seismically designed, and of those buildings ~ 60% have been designed to low code, ~ 25% to moderate code and 15% to high code. This seismic design model aims at being a dynamic source of information that will be continuously updated with additional feedback from local experts and datasets. To this end, all of the data has been made openly available as shapefiles on a GitLab repository.

High perceived isolation and reduced social support affect headache impact levels in migraine after the Covid-19 outbreak: A cross sectional survey on chronic and episodic patients.

Abstract: BackgroundPsychosocial variables are key factors influencing psycho-physical equilibrium in migraine patients. Social isolation and vulnerability to stressors may prevent efficient psycholo...

Decreased information processing speed and decision-making performance in alcohol use disorder: combined neurostructural evidence from VBM and TBSS.

Abstract: Alcohol Use Disorder (AUD) is a chronic relapsing condition characterized by excessive alcohol consumption despite its multifaceted adverse consequences, associated with impaired performance in several cognitive domains including decision-making. While choice deficits represent a core component of addictive behavior, possibly consecutive to brain changes preceding the onset of the addiction cycle, the evidence on grey-matter and white-matter damage underlying abnormal choices in AUD is still limited. To fill this gap, we assessed the neurostructural bases of decision-making performance in 22 early-abstinent alcoholic patients and 18 controls, by coupling the Cambridge Gambling Task (CGT) with quantitative magnetic resonance imaging metrics of grey-matter density and white-matter integrity. Regardless of group, voxel based morphometry highlighted an inverse relationship between deliberation time and grey-matter density, with alcoholics displaying slower choices related to grey-matter atrophy in key nodes of the motor control network. In particular, grey-matter density in the supplementary motor area, reduced in alcoholic patients, explained a significant amount of variability in their increased deliberation time. Tract-based spatial statistics revealed a significant relationship between CGT deliberation time and all white-matter indices, involving the most relevant commissural, projection and associative tracts. The lack of choice impairments other than increased deliberation time highlights reduced processing speed, mediated both by grey-matter and white-matter alterations, as a possible marker of a generalized executive impairment extending to the output stages of decision-making. These results pave the way to further studies aiming to tailor novel rehabilitation strategies and assess their functional outcomes.