Institution
Sigma-Tau
Company•Mendrisio, Switzerland•
About: Sigma-Tau is a company organization based out in Mendrisio, Switzerland. It is known for research contribution in the topics: Carnitine & Acetylcarnitine. The organization has 1079 authors who have published 1527 publications receiving 37822 citations.
Topics: Carnitine, Acetylcarnitine, Heart failure, Camptothecin, Receptor
Papers published on a yearly basis
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569 citations
TL;DR: Results indicated that changes in the rate of lipid oxidation in selective hypothalamic neurons signaled nutrient availability to the hypothalamus, which in turn modulated the exogenous and endogenous inputs of nutrients into the circulation.
Abstract: Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production
520 citations
TL;DR: The findings of significant linkage of the α-adducin locus to essential hypertension and greater sensitivity to changes in sodium balance among patients with the mutant allele suggest that α- adducin is associated with a salt-sensitive form of essential hypertension.
519 citations
TL;DR: Iodoxy benzoic acid (IBX) smoothly oxidizes primary and secondary alcohols to aldehydes and ketones, respectively, without any oxidative cleavage of the glycol CC bond as discussed by the authors.
436 citations
TL;DR: This review will focus on recent advances on the essentiality of these molecules and on their interplay in cell physiology, leading to new perspective in different therapeutic fields.
Abstract: Dietary polyunsaturated fatty acids (PUFA) have effects on diverse physiological processes impacting normal health and chronic diseases, such as the regulation of plasma lipid levels, cardiovascular and immune function, insulin action and neuronal development and visual function. Ingestion of PUFA will lead to their distribution to virtually every cell in the body with effects on membrane composition and function, eicosanoid synthesis, cellular signaling and regulation of gene expression. Cell specific lipid metabolism, as well as the expression of fatty acid-regulated transcription factors, likely play an important role in determining how cells respond to changes in PUFA composition. This review will focus on recent advances on the essentiality of these molecules and on their interplay in cell physiology, leading to new perspective in different therapeutic fields.
434 citations
Authors
Showing all 1079 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Piero Anversa | 115 | 412 | 60220 |
| Anthony A. Amato | 105 | 911 | 57881 |
| Massimo Zeviani | 104 | 478 | 39743 |
| Luigina Romani | 93 | 384 | 33842 |
| Gennaro Ciliberto | 77 | 483 | 25888 |
| Francesco Bistoni | 74 | 340 | 17890 |
| Marco Presta | 73 | 352 | 18422 |
| Marina Noris | 70 | 234 | 19250 |
| Samuel Gershon | 61 | 366 | 14056 |
| Giorgio Casari | 59 | 160 | 18048 |
| Annunciata Vecchi | 59 | 150 | 17108 |
| Luca Battistini | 58 | 171 | 11717 |
| Giuseppe Bianchi | 55 | 290 | 10708 |
| Giovanni Palmisano | 55 | 458 | 11825 |
| Andrea Doni | 53 | 99 | 11335 |