Taylors University

About: Taylors University is a based out in . It is known for research contribution in the topics: Tourism & Population. The organization has 1513 authors who have published 2954 publications receiving 33603 citations.

Application of Proteases for the Production of Bioactive Peptides

Abstract: Over the past few decades, the use of enzyme preparation in food processing has increased tremendously because it is a green technology. Plants, animals, and microorganisms are important sources of enzyme preparation, containing an active enzyme or a mixture of two or more active enzymes. Alcalase, Flavourzyme, and Protamex are among the proteases intentionally added to foodstuffs as processing aids to impart flavor, taste, and textural changes in processed food. Recently, these proteases have gained the attention of the food industry for products of protein hydrolysis in other food applications, particularly in the production of bioactive peptides having physiological functions. Numerous food and food processing by-products high in protein content as the substrates for the proteases have been extensively studied. The potential of bioactive peptides in reducing the worldwide epidemic of noncommunicable diseases (NCDs) seems promising in a significant amount of the studies conducted. Tackling NCDs, which account for millions of premature deaths annually, constitutes one of the major challenges for development in modern days. The gap between laboratory experiment and industrial product realization must be filled to bring about an improvement in nutritional status and the physical well-being of people. This chapter describes proteases from fundamental to recent updates as well as discusses the feasibility and possible challenges of the industry application of proteases for the production of bioactive peptides. The potential roles of proteases in combating food insecurity and mitigating environmental issues by ensuring optimum utilization of food and food processing by-products will be highlighted.

Microalgae as Potential Anti-Inflammatory Natural Product Against Human Inflammatory Skin Diseases.

Abstract: The skin is the first line of defense against pathogen and other environmental pollutant. The body is constantly exposed to reactive oxygen species (ROS) that stimulates inflammatory process in the skin. Many studies have linked ROS to various inflammatory skin diseases. Patients with skin diseases face various challenges with inefficient and inappropriate treatment in managing skin diseases. Overproduction of ROS in the body will result in oxidative stress which will lead to various cellular damage and alter normal cell function. Multiple signaling pathways are seen to have significant effects during ROS-mediated oxidative stress. In this review, microalgae have been selected as a source of natural-derived antioxidant to combat inflammatory skin diseases that are prominent in today’s society. Several studies have demonstrated that bioactive compounds isolated from microalgae have anti-inflammation and anti-oxidative properties that can help remedy various skin diseases. These compounds are able to inhibit production of pro-inflammatory cytokines and reduce the expression of inflammatory genes. Bioactive compounds from microalgae work in action by altering enzyme activities, regulating cellular activities, targeting major signaling pathways related to inflammation.