Institution
University of Catania
Education•Catania, Italy•
About: University of Catania is a education organization based out in Catania, Italy. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 14599 authors who have published 41195 publications receiving 1032705 citations. The organization is also known as: Università degli Studi di Catania & Universita degli Studi di Catania.
Papers published on a yearly basis
Papers
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TL;DR: In this paper, a data sample of PbPb collisions collected in 2011 at a nucleon-nucleon center-of-mass energy of √sNN = 2.76 TeV corresponding to an integrated luminosity of 150μb^(−1) is used.
Abstract: The jet fragmentation function of inclusive jets with transverse momentum p_T above 100GeV/c in PbPb collisions has been measured using reconstructed charged particles with p_T above 1GeV/c in a cone of radius 0.3 around the jet axis. A data sample of PbPb collisions collected in 2011 at a nucleon-nucleon center-of-mass energy of √sNN = 2.76 TeV corresponding to an integrated luminosity of 150μb^(−1) is used. The results for PbPb collisions as a function of collision centrality and jet transverse momentum are compared to reference distributions based on pp data collected at the same center-of-mass energy in 2013, with an integrated luminosity of 5.3pb^(−1). A centrality-dependent modification of the fragmentation function is found. For the most central collisions, a significant enhancement is observed in the PbPb/pp fragmentation function ratio for charged particles with p_T less than 3GeV/c. This enhancement is observed for all jet p_T bins studied.
197 citations
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TL;DR: In this article, the authors defined heterogeneity of adult-onset autoimmune diabetes based on characterization of GAD antibodies (GADAs) and further characterized for GADA titer, antibodies to thyroid peroxidase (TPO), and HLA DRB1-DQB1 polymorphisms.
Abstract: OBJECTIVE —The aim of the present study was to define heterogeneity of adult-onset autoimmune diabetes based on characterization of GAD antibodies (GADAs). RESEARCH DESIGN AND METHODS —Patients enrolled in a nationwide survey, the Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study, have been screened for GADAs and IA-2 antibodies (IA-2As) and further characterized for GADA titer, antibodies to thyroid peroxidase (TPO), and HLA DRB1-DQB1 polymorphisms. RESULTS —Of 4,250 consecutive type 2 diabetic patients, 4.5% had either GADAs and/or IA-2As. Patients with autoimmune diabetes showed a clinical phenotype significantly different from that of type 2 diabetes, including higher fasting glucose and A1C, lower BMI and uric acid, lower prevalence of metabolic syndrome and its components, and higher frequency of TPO antibodies. More interestingly, analysis of GADA titers showed a bimodal distribution that identified two subgroups of patients with high (>32 GADA arbitrary units) and low (≤32 GADA arbitrary units) GADA titers. Compared with those with low GADA titers, patients with high GADA titers had more prominent traits of insulin deficiency and a profile of more severe autoimmunity resulting in higher A1C, lower BMI, a lower prevalence of metabolic syndrome and its components ( P P P = 0.001), and a decreasing frequency of DQB1*0602 and DRB1*0403 (from type 2 to low and to high GADA titer autoimmune diabetes; P CONCLUSIONS —GADA titers identify two subgroups of patients with adult-onset autoimmune diabetes having distinct clinical, autoimmune, and genetic features.
197 citations
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TL;DR: A method that tries to take into account information about discontinuities or sharp luminance variations while doubling the input picture is proposed, which is competitive both for quality and efficiency with bicubic interpolation.
197 citations
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S. Chatrchyan1, Vardan Khachatryan1, Albert M. Sirunyan1, Armen Tumasyan1 +3905 more•Institutions (138)
TL;DR: Spectra of identified charged hadrons are measured in pp collisions at the LHC for sqrt(s) = 0.9, 2.76, and 7 TeV as mentioned in this paper.
Abstract: Spectra of identified charged hadrons are measured in pp collisions at the LHC for sqrt(s) = 0.9, 2.76, and 7 TeV. Charged pions, kaons, and protons in the transverse-momentum range pt approximately 0.1-1.7 GeV and for rapidities abs(y) < 1 are identified via their energy loss in the CMS silicon tracker. The average pt increases rapidly with the mass of the hadron and the event charged-particle multiplicity, independently of the center-of-mass energy. The fully corrected pt spectra and integrated yields are compared to various tunes of the PYTHIA6 and PYTHIA8 event generators.
196 citations
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TL;DR: Understanding of the putative mechanisms by which cytokines may mediate beneficial and harmful effects, through activation of phagocytic cells, could help to develop new treatment strategies, regardless of the emergence of parasite multidrug resistance.
Abstract: Summary Malaria is still a major cause of severe disease which is responsible for millions of deaths, mostly in children under 5 years old, in tropical countries, especially sub-Saharan Africa. Complications of severe anaemia and cerebral malaria are thought to be the major cause of morbidity and mortality but recent evidence suggests that the host's immunological response could also contribute to the pathophysiology of the disease in human beings. Intensive studies of the immune response to malaria parasites in human beings have provided a wealth of information about the cells and cytokines implicated in the pathophysiology of survival and fatal outcome in severe infections. This review focuses on the pivotal role of macrophages and other important cellular effectors, molecules, and cytokines involved in the activation of the immune response at the different stages of human falciparum malaria. Our understanding of the putative mechanisms by which cytokines may mediate beneficial and harmful effects, through activation of phagocytic cells, could help to develop new treatment strategies, regardless of the emergence of parasite multidrug resistance.
196 citations
Authors
Showing all 14771 results
Name | H-index | Papers | Citations |
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Napoleone Ferrara | 167 | 494 | 140647 |
Tobin J. Marks | 159 | 1621 | 111604 |
Susan O'Brien | 145 | 1509 | 87813 |
Stephen T. Holgate | 142 | 870 | 82345 |
Y. Choi | 141 | 1631 | 98709 |
Michael J. Keating | 140 | 1169 | 76353 |
Tiziano Rovelli | 135 | 1441 | 90518 |
Francesco Navarria | 135 | 1535 | 91427 |
Francesca Romana Cavallo | 135 | 1571 | 92392 |
Alessia Tricomi | 133 | 1446 | 92375 |
Burak Bilki | 132 | 1227 | 83478 |
Andrea Castro | 132 | 1500 | 90019 |
Paolo Capiluppi | 131 | 1544 | 89643 |
Daniele Bonacorsi | 130 | 1381 | 85994 |
Vitaliano Ciulli | 129 | 1171 | 82045 |