Showing papers in "American Heart Journal in 1999"

TL;DR: It is suggested that changes in cardiac autonomic function reflected by changes in mean HR and HRV may be part of the pathophysiologic mechanisms or pathways linking cardiovascular mortality and particulate air pollution.

TL;DR: Among patients undergoing diagnostic cardiac catheterization, transradial access leads to improved quality of life after the procedure, is strongly preferred by patients, and reduces hospital costs.

TL;DR: Men had twice the prevalence of invasive cardiac procedures as did women during hospitalization and the growing burden of heart failure can be expected to increase during the next decade unless innovative interventions and primary and secondary prevention strategies are implemented.

TL;DR: Dobutamine use at the time of randomization was associated with a higher 6-month mortality rate and this effect persisted after adjustment for baseline differences, challenges the concept that continuous intravenous dobutamine is beneficial to advanced heart failure patients with respect to survival.

TL;DR: The diagnostic rate achieved with biopsy in cardiac sarcoidosis is low; the patients with sarcoIDosis and evidence of significant cardiac involvement should be treated for cardiac sarCOidosis despite negative myocardial biopsies for this disease.

TL;DR: This study is the first to report the detection of 2 major odontopathogens, P gingivalis and S sanguis, in atherosclerotic plaques, and the immunolocalization of these micro-organisms within unstable plaque regions and their association with plaque ulceration, thrombosis, and apoptosis in vascular cells are intriguing.

TL;DR: Important consequences of postischemic reperfusion are reversible contractile dysfunction ("stunning"), which is mostly caused by oxygen radical attack, and impairment to flow at the microvascular level ("no-reflow") secondary to neutrophil plugging and vasoconstriction.

TL;DR: Pooling of the data available from randomized controlled trials indicates that an average reduction of 12 to 13 mm Hg in systolic blood pressure over 4 years of follow-up is associated with a 21% reduction in coronary heart disease, 37% reduction In stroke, 25% reductionIn total cardiovascular mortality, and 13% reductionin all-cause mortality rates.

TL;DR: In patients undergoing intensive treatment for heart failure, aggravated renal dysfunction is common and clinically significant and the relation among baseline factors, ARD, and worsened outcome may reflect complex cardiorenal interactions.

TL;DR: Plasma BNP concentration may be chronically reduced by tailored vasodilator therapy in CHF and was associated with more profound inhibition of the renin-angiotensin-aldosterone system and significant fall in heart rate when compared with empiric therapy.

TL;DR: An integrated view of the role of arterial blood pressure in cardiovascular physiology should consider both the steady and pulsatile components, which include ventricle performance, peripheral resistance, pulse wave velocity, and the timing of pulse wave reflections.

TL;DR: The disparate findings of higher hospitalization and rehospitalization rates and lower mortality rates among African Americans than whites may represent differences in the underlying pathophysiology of CHF in these groups or differences in access to quality care.

TL;DR: The determination of ED was found to be a sensitive and specific screening test to predict the presence of CAD, and a high sensitivity for FMD% was found.

TL;DR: Paraprosthetic aortic leaks detected early after surgery, in the absence of valve infection, are common, are usually small, and have a benign course, however, the development of new, usually severe, regurgitation should raise the suspicion of prosthetic valve endocarditis or bioprosthetic valve failure.

TL;DR: Preliminary findings from the Dental Atherosclerosis Risk in Communities study indicate that periodontal disease is associated with carotid intimal-medial wall thickness, a measure of subclinical atherosclerosis, adjusting for factors known to be associated with both conditions.

TL;DR: The observed pattern of differences is consistent with the contention that demographic, cultural, and/or socioeconomic barriers exist that impede rapid care seeking.

TL;DR: The results of this study indicated that exercise and adenosine stress myocardial perfusion SPECT are valuable for risk stratification and management of patients with diabetes.

TL;DR: The SHOCK trial is testing the hypothesis that a direct invasive strategy of emergency revascularization for patients with cardiogenic shock complicating acute MI will reduce 30-day all-cause mortality rate by 20 absolute percentage points compared with initial medical stabilization.

TL;DR: Exercise training increases total heart rate variability in normal older adults and the most marked alterations are in nocturnal heart rate, which is stable over a 1-year period in older adults who do not alter their activity level.

TL;DR: These findings suggest that a multidisciplinary program of patient education, monitoring, and physician notification can reduce resource use in patients with heart failure managed in a community setting.

TL;DR: Enalapril use caused a 33% increase in the risk of decreased renal function in patients with CHF, and older age, diuretic therapy, and diabetes were associated with decreases renal function, whereas beta-blocker therapy and higher ejection fraction were renoprotective.

TL;DR: Concern is raised about the potential adverse effects of long-acting nitrate therapy in chronic coronary disease because of its association with a significantly increased mortality risk in patients who had recovered from an acute coronary event.

TL;DR: Findings provide theoretical support for the use of long-acting agents to provide adequate anti-ischemic protection during the higher risk morning hours in patients already taking anti-ISChemic medications.

TL;DR: Major depression in patients hospitalized after myocardial infarction is a significant univariable predictor of death at 12 months, although it was not a statistically significant predictor after adjusting for other variables, and hostility is not a predictor ofdeath.

TL;DR: In this article, a risk assessment prognostic algorithm of 30-day mortality, including clinical and hemodynamic data prospectively collected among patients with cardiogenic shock in the 41,021-patient Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries (GUSTO-I) trial, was developed.

TL;DR: Notoriously difficult to diagnose and distinguish from restrictive cardiomyopathy (RCM), the use of cardiac catheterization, echocardiography, central venous and transvalvular Doppler measurements, and magnetic resonance imaging should secure the diagnosis in most cases, eliminating the need for diagnostic thoracotomy.

TL;DR: The data suggest that a specialized outpatient clinic can improve practice patterns in patients with CHF and the high mortality risk in CHF with preserved systolic function suggests the need to find efficacious (and effective) therapies for this condition.

TL;DR: Six-month intermittent low-dose dobutamine administration was well tolerated by patients with severe CHF; it did not improve the functional status and did not significantly increase the mortality rate as found with higherDobutamine doses in other studies.

TL;DR: In this paper, the authors evaluated the safety of several doses of a new thrombolytic, TNK tissue-plasminogen activator (tPA), given as a single bolus to patients with acute myocardial infarction.